User profiles for Maria F. Gencoglu

Maria Gencoglu

University of the pacific
Verified email at pacific.edu
Cited by 340

Comparative study of multicellular tumor spheroid formation methods and implications for drug screening

MF Gencoglu, LE Barney, CL Hall… - ACS biomaterials …, 2018 - ACS Publications
Improved in vitro models are needed to better understand cancer progression and bridge
the gap between in vitro proof-of-concept studies, in vivo validation, and clinical application. …

Applicability of drug response metrics for cancer studies using biomaterials

EA Brooks, S Galarza, MF Gencoglu… - … of the Royal …, 2019 - royalsocietypublishing.org
Bioengineers have built models of the tumour microenvironment (TME) in which to study cell–cell
interactions, mechanisms of cancer growth and metastasis, and to test new therapies. …

[HTML][HTML] An omentum-inspired 3D PEG hydrogel for identifying ECM-drivers of drug resistant ovarian cancer

EA Brooks, MF Gencoglu, DC Corbett… - APL …, 2019 - pubs.aip.org
Gencoglu … 1(f)]. These results allowed for subsequent drug screening experiments in
these platforms. … For cell seeding, microwell surfaces were UV sterilized for 30 min …

A study on the cytotoxicity of carbon-based materials

D Saha, CL Heldt, MF Gencoglu… - Materials Science and …, 2016 - Elsevier
With an aim to understand the origin and key contributing factors towards carbon-induced
cytotoxicity, we have studied five different carbon samples with diverse surface area, pore …

Biocompatibility of soft-templated mesoporous carbons

MF Gencoglu, A Spurri, M Franko, J Chen… - … Applied Materials & …, 2014 - ACS Publications
Soft-templated mesoporous carbon is morphologically a non-nano type of carbon. It is a
relatively newer variety of biomaterial, which has already demonstrated its successful role in …

Complementary, semiautomated methods for creating multidimensional PEG-based biomaterials

EA Brooks, LE Jansen, MF Gencoglu… - Acs Biomaterials …, 2018 - ACS Publications
Tunable biomaterials that mimic selected features of the extracellular matrix (ECM) such as
its stiffness, protein composition, and dimensionality are increasingly popular for studying …

Enveloped virus flocculation and removal in osmolyte solutions

MF Gencoglu, CL Heldt - Journal of Biotechnology, 2015 - Elsevier
Our ability to reduce infectious disease burden throughout the world has been greatly
improved by the creation of vaccines. However, worldwide immunization rates are low. The two …

Porcine parvovirus flocculation and removal in the presence of osmolytes

MF Gencoglu, E Pearson, CL Heldt - Journal of Biotechnology, 2014 - Elsevier
Viruses can be modified into viral vaccines or gene therapy vectors in order to treat acquired
or genetic diseases. To satisfy the current market demand, an improvement in current …

Biomaterials in mechano-oncology: means to tune materials to study cancer

SR Peyton, MF Gencoglu, S Galarza… - Biomechanics in …, 2018 - Springer
ECM stiffness is emerging as a prognostic marker of tumor aggression or potential for relapse.
However, conflicting reports muddle the question of whether increasing or decreasing …

[BOOK][B] Purification and effectiveness of vaccines and antiviral compounds

MF Gencoglu - 2014 - search.proquest.com
Viral infections account for over 13 millions deaths per year. Antiviral drugs and vaccines are
the most effective method to treat viral diseases. Antiviral compounds have revolutionized …