[HTML][HTML] SARS-CoV-2 spike alterations enhance pseudoparticle titers and replication-competent VSV-SARS-CoV-2 virus

…, AR Jimenez, MD Acciani, MF Lay Mendoza… - Viruses, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the
most recent global pandemic that has caused more than a million deaths around the world…

[HTML][HTML] Monitoring viral entry in real-time using a luciferase recombinant vesicular stomatitis virus producing SARS-CoV-2, EBOV, LASV, CHIKV, and VSV …

MF Lay Mendoza, MD Acciani, CN Levit, C Santa Maria… - Viruses, 2020 - mdpi.com
Viral entry is the first stage in the virus replication cycle and, for enveloped viruses, is mediated
by virally encoded glycoproteins. Viral glycoproteins have different receptor affinities and …

Ebola virus requires phosphatidylserine scrambling activity for efficient budding and optimal infectivity

MD Acciani, MF Lay Mendoza, KE Havranek… - Journal of …, 2021 - Am Soc Microbiol
Ebola virus (EBOV) attaches to target cells using two categories of cell surface receptors: C-type
lectins and phosphatidylserine (PS) receptors. PS receptors typically bind to apoptotic …

Ebola virus requires phosphatidylserine scrambling activity for efficient budding and optimal infectivity

MD Acciani, MF Lay-Mendoza, KE Havranek… - bioRxiv, 2020 - biorxiv.org
Ebola virus (EBOV) interacts with cells using two categories of cell surface receptors, C-type
lectins and phosphatidylserine (PS) receptors. PS receptors typically bind to apoptotic cell …

A real-time luciferase assay using vesicular stomatitis virus to study entry of hemorrhagic fever viruses

MFL Mendoza - 2020 - search.proquest.com
Since viral hemorrhagic fever (VHF) viruses such as Lassa virus (LASV) and Ebolavirus (EBOV)
are classified as biosafety level 4 (BSL-4) pathogens, research with these viruses are …

Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine

JM Reyes Ballista, AJ Hoover, JT Noble, MD Acciani… - bioRxiv, 2024 - biorxiv.org
T-cell immunoglobin and mucin domain protein-1 (TIM-1) mediates entry of Chikungunya virus
(CHIKV) into some mammalian cells through the interaction with envelope phospholipids. …

[HTML][HTML] Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells

JM Reyes Ballista, KL Miazgowicz… - Frontiers in Cell and …, 2023 - frontiersin.org
Chikungunya virus (CHIKV) is the causative agent of the human disease chikungunya fever,
characterized by debilitating acute and chronic arthralgia. No licensed vaccines or antivirals …

[HTML][HTML] Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target

I García-Dorival, MÁ Cuesta-Geijo, L Barrado-Gil… - Antiviral Research, 2021 - Elsevier
Niemann-Pick type C1 (NPC1) receptor is an endosomal membrane protein that regulates
intracellular cholesterol traffic. This protein has been shown to play an important role for …

[HTML][HTML] Application of pseudotyped virus particles to monitor Ebola virus and SARS-CoV-2 viral entry in human cell lines

M Eichler, E Aksi, J Pfeilschifter, G Imre - STAR protocols, 2021 - Elsevier
Experimental work on highly pathogenic viruses such as Ebola virus (EBOV) and severe
acute respiratory syndrome coronavirus-2 requires high-level biosafety facilities. Here, we …

Temperate conditions limit zika virus genome replication

B Tesla, JS Powers, Y Barnes, S Lakhani… - Journal of …, 2022 - Am Soc Microbiol
Zika virus is a mosquito-borne flavivirus known to cause severe birth defects and
neuroimmunological disorders. We have previously demonstrated that mosquito transmission of Zika …