Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome
Z Misulovin, YB Schwartz, XY Li, TG Kahn, M Gause… - Chromosoma, 2008 - Springer
The cohesin complex is a chromosomal component required for sister chromatid cohesion
that is conserved from yeast to man. The similarly conserved Nipped-B protein is needed for …
that is conserved from yeast to man. The similarly conserved Nipped-B protein is needed for …
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
Histone H3 lysine 4 monomethylation (H3K4me1) is an evolutionarily conserved feature of
enhancer chromatin catalyzed by the COMPASS-like methyltransferase family, which …
enhancer chromatin catalyzed by the COMPASS-like methyltransferase family, which …
[HTML][HTML] Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes
CA Schaaf, Z Misulovin, M Gause, A Koenig… - PLoS …, 2013 - journals.plos.org
Cohesin is crucial for proper chromosome segregation but also regulates gene transcription
and organism development by poorly understood mechanisms. Using genome-wide assays …
and organism development by poorly understood mechanisms. Using genome-wide assays …
Insulation of enhancer-promoter communication by a gypsy transposon insert in the Drosophila cut gene: cooperation between suppressor of hairy-wing and modifier …
M Gause, P Morcillo, D Dorsett - Molecular and cellular biology, 2001 - Am Soc Microbiol
The Drosophila mod (mdg4) gene products counteract heterochromatin-mediated silencing
of the white gene and help activate genes of the bithorax complex. They also regulate the …
of the white gene and help activate genes of the bithorax complex. They also regulate the …
[HTML][HTML] Regulation of the Drosophila Enhancer of split and invected-engrailed Gene Complexes by Sister Chromatid Cohesion Proteins
…, YB Schwartz, TG Kahn, V Pirrotta, M Gause… - PloS one, 2009 - journals.plos.org
The cohesin protein complex was first recognized for holding sister chromatids together and
ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the …
ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the …
[PDF][PDF] Cohesin selectively binds and regulates genes with paused RNA polymerase
A Fay, Z Misulovin, J Li, CA Schaaf, M Gause… - Current Biology, 2011 - cell.com
Background The cohesin complex mediates sister chromatid cohesion and regulates gene
transcription. Prior studies show that cohesin preferentially binds and regulates genes that …
transcription. Prior studies show that cohesin preferentially binds and regulates genes that …
Dosage-sensitive regulation of cohesin chromosome binding and dynamics by Nipped-B, Pds5, and Wapl
M Gause, Z Misulovin, A Bilyeu… - Molecular and cellular …, 2010 - Am Soc Microbiol
The cohesin protein complex holds sister chromatids together to ensure proper chromosome
segregation upon cell division and also regulates gene transcription. Partial loss of the …
segregation upon cell division and also regulates gene transcription. Partial loss of the …
Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling
…, A Ilvarsonn, J Schneider, M Gause… - Proceedings of the …, 2006 - National Acad Sciences
The Rtf1 subunit of the Paf1 complex is required for proper monoubiquitination of histone
H2B and methylation of histone H3 on lysines 4 (H3K4) and 79 in yeast Saccharomyces …
H2B and methylation of histone H3 on lysines 4 (H3K4) and 79 in yeast Saccharomyces …
Polycomb repressive complex 1 modifies transcription of active genes
M Pherson, Z Misulovin, M Gause… - Science …, 2017 - science.org
This study examines the role of Polycomb repressive complex 1 (PRC1) at active genes. The
PRC1 and PRC2 complexes are crucial for epigenetic silencing during development of an …
PRC1 and PRC2 complexes are crucial for epigenetic silencing during development of an …
Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila
M Pherson, Z Misulovin, M Gause, D Dorsett - Genome research, 2019 - genome.cshlp.org
Cohesin consists of the SMC1-SMC3-Rad21 tripartite ring and the SA protein that interacts
with Rad21. The Nipped-B protein loads cohesin topologically around chromosomes to …
with Rad21. The Nipped-B protein loads cohesin topologically around chromosomes to …