Rad51 replication fork recruitment is required for DNA damage tolerance
…, AM Muñoz‐Cabello, MJ Cabello‐Lobato… - The EMBO …, 2013 - embopress.org
Homologous recombination (HR) is essential for genome integrity. Recombination proteins
participate in tolerating DNA lesions that interfere with DNA replication, but can also …
participate in tolerating DNA lesions that interfere with DNA replication, but can also …
[PDF][PDF] Physical interactions between MCM and Rad51 facilitate replication fork lesion bypass and ssDNA gap filling by non-recombinogenic functions
MJ Cabello-Lobato, C Gonzalez-Garrido… - Cell Reports, 2021 - cell.com
The minichromosome maintenance (MCM) helicase physically interacts with the recombination
proteins Rad51 and Rad52 from yeast to human cells. We show, in Saccharomyces …
proteins Rad51 and Rad52 from yeast to human cells. We show, in Saccharomyces …
Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining
MJ Cabello-Lobato, M Jenner… - Nucleic acids …, 2022 - academic.oup.com
SUMOylation is critical for numerous cellular signalling pathways, including the maintenance
of genome integrity via the repair of DNA double-strand breaks (DSBs). If misrepaired, …
of genome integrity via the repair of DNA double-strand breaks (DSBs). If misrepaired, …
[HTML][HTML] SAMHD1 sheds moonlight on DNA double-strand break repair
MJ Cabello-Lobato, S Wang, CK Schmidt - Trends in Genetics, 2017 - cell.com
SAMHD1 (sterile α motif and histidine (H) aspartate (D) domain-containing protein 1) is
known for its antiviral activity of hydrolysing deoxynucleotides required for virus replication. …
known for its antiviral activity of hydrolysing deoxynucleotides required for virus replication. …
[HTML][HTML] Crosstalk between chromatin structure, cohesin activity and transcription
…, M Barrientos-Moreno, MJ Cabello-Lobato… - Epigenetics & …, 2019 - Springer
Background A complex interplay between chromatin and topological machineries is critical
for genome architecture and function. However, little is known about these reciprocal …
for genome architecture and function. However, little is known about these reciprocal …
Defective histone supply causes condensin-dependent chromatin alterations, SAC activation and chromosome decatenation impairment
M Murillo-Pineda, MJ Cabello-Lobato… - Nucleic Acids …, 2014 - academic.oup.com
The structural organization of chromosomes is essential for their correct function and
dynamics during the cell cycle. The assembly of DNA into chromatin provides the substrate for …
dynamics during the cell cycle. The assembly of DNA into chromatin provides the substrate for …
[HTML][HTML] 1H, 13C, 15N backbone resonance assignment for the 1–164 construct of human XRCC4
MJ Cabello-Lobato, CK Schmidt, MJ Cliff - Biomolecular NMR …, 2021 - Springer
DNA double-strand breaks (DSBs) represent the most cytotoxic DNA lesions, as—if mis- or
unrepaired—they can cause cell death or lead to genome instability, which in turn can cause …
unrepaired—they can cause cell death or lead to genome instability, which in turn can cause …
In vivo binding of recombination proteins to non-DSB DNA lesions and to replication forks
R González-Prieto, MJ Cabello-Lobato… - … : Methods and Protocols, 2021 - Springer
Homologous recombination (HR) has been extensively studied in response to DNA double-strand
breaks (DSBs). In contrast, much less is known about how HR deals with DNA lesions …
breaks (DSBs). In contrast, much less is known about how HR deals with DNA lesions …
Papel del Cdc7 en la regulación de la recombinación homóloga durante la tolerancia a daños replicativos
MJC Lobato - 2016 - produccioncientifica.usal.es
La tolerancia a daños en el ADN (DDT, DNA damage tolerance) es una compleja red de
mecanismos que facilita el avance de las horquillas replicativas sobre lesiones que las …
mecanismos que facilita el avance de las horquillas replicativas sobre lesiones que las …
Cdc7, Rad53 and Asf1 stabilize Rad52 binding to replicative DNA damage
MJ Cabello-Lobato, R González-Prieto, F Prado - 2014 - digital.csic.es
The response to DNA lesions that impair the advance of replication forks relies on DNA damage
tolerance (DDT) mechanisms, which facilitate fork bypass across the lesions and repair …
tolerance (DDT) mechanisms, which facilitate fork bypass across the lesions and repair …