Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer
VM Arlt, M Stiborová, J vom Brocke, ML Simoes… - …, 2007 - academic.oup.com
Balkan endemic nephropathy (BEN) is found in certain rural areas of the Balkans and affects
at least 25 000 inhabitants. Of the many hypotheses on BEN, the Aristolochia hypothesis …
at least 25 000 inhabitants. Of the many hypotheses on BEN, the Aristolochia hypothesis …
[HTML][HTML] CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection
Plasmodium relies on numerous agonists during its journey through the mosquito vector,
and these agonists represent potent targets for transmission-blocking by either inhibiting or …
and these agonists represent potent targets for transmission-blocking by either inhibiting or …
[HTML][HTML] Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor …
…, M Robson, E Poon, ML Simões… - The Journal of …, 2012 - Am Soc Clin Investig
Increased expression of the regulatory subunit of HIFs (HIF-1α or HIF-2α) is associated with
metabolic adaptation, angiogenesis, and tumor progression. Understanding how HIFs are …
metabolic adaptation, angiogenesis, and tumor progression. Understanding how HIFs are …
Mosquito gut antiparasitic and antiviral immunity
Mosquitoes are responsible for the transmission of diseases with a serious impact on global
human health, such as malaria and dengue. All mosquito-transmitted pathogens complete …
human health, such as malaria and dengue. All mosquito-transmitted pathogens complete …
[HTML][HTML] A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration
BACKGROUND & AIMS: Hepatitis C virus (HCV) causes progressive liver disease and is a
major risk factor for the development of hepatocellular carcinoma (HCC). However, the role of …
major risk factor for the development of hepatocellular carcinoma (HCC). However, the role of …
[HTML][HTML] Emissivity of building materials for infrared measurements
Infrared thermography (IRT) is a technique increasingly used in building inspection. If in many
applications it is sufficient to analyze the thermal patterns, others exist in which the exact …
applications it is sufficient to analyze the thermal patterns, others exist in which the exact …
Mosquito transgenesis for malaria control
Malaria is one of the deadliest diseases. Because of the ineffectiveness of current malaria-control
methods, several novel mosquito vector-based control strategies have been proposed …
methods, several novel mosquito vector-based control strategies have been proposed …
Versatile transgenic multistage effector-gene combinations for Plasmodium falciparum suppression in Anopheles
The malaria parasite’s complex journey through the Anopheles mosquito vector provides
multiple opportunities for targeting Plasmodium with recombinant effectors at different …
multiple opportunities for targeting Plasmodium with recombinant effectors at different …
Diverse host and restriction factors regulate mosquito–pathogen interactions
Mosquitoes transmit diseases that seriously impact global human health. Despite extensive
knowledge of the life cycles of mosquito-borne parasites and viruses within their hosts, …
knowledge of the life cycles of mosquito-borne parasites and viruses within their hosts, …
Additional Feeding Reveals Differences in Immune Recognition and Growth of Plasmodium Parasites in the Mosquito Host
Mosquitoes may feed multiple times during their life span in addition to those times needed
to acquire and transmit malaria. To determine the impact of subsequent blood feeding on …
to acquire and transmit malaria. To determine the impact of subsequent blood feeding on …