User profiles for Maria Lopopolo
 | Maria LopopoloInstitute Pasteur, Paris Verified email at pasteur.fr Cited by 287 |
[PDF][PDF] A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
…, A Lee, A Linder, T Lockett, L Lonie, M Lopopolo… - Cell, 2022 - cell.com
Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete
description of specific immune biomarkers. We present here a comprehensive multi-omic …
description of specific immune biomarkers. We present here a comprehensive multi-omic …
[HTML][HTML] Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS
…, P Siejka-Zielińska, C Weldon, H Roberts, M Lopopolo… - Genome biology, 2020 - Springer
We present long-read Tet-assisted pyridine borane sequencing (lrTAPS) for targeted base-resolution
sequencing of DNA methylation and hydroxymethylation in regions up to 10 kb …
sequencing of DNA methylation and hydroxymethylation in regions up to 10 kb …
[HTML][HTML] Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in …
…, A Linder, T Lockett, L Lonie, M Lopopolo… - The Lancet Digital …, 2022 - thelancet.com
Background Direct evaluation of vascular inflammation in patients with COVID-19 would
facilitate more efficient trials of new treatments and identify patients at risk of long-term …
facilitate more efficient trials of new treatments and identify patients at risk of long-term …
[HTML][HTML] Short and long-read genome sequencing methodologies for somatic variant detection; genomic analysis of a patient with diffuse large B-cell lymphoma
HE Roberts, M Lopopolo, AT Pagnamenta… - Scientific Reports, 2021 - nature.com
Recent advances in throughput and accuracy mean that the Oxford Nanopore Technologies
PromethION platform is a now a viable solution for genome sequencing. Much of the …
PromethION platform is a now a viable solution for genome sequencing. Much of the …
A study of the peopling of Greenland using next generation sequencing of complete mitochondrial genomes
Objectives The Greenlandic population history is characterized by a number of migrations of
people of various ethnicities. In this work, the analysis of the complete mtDNA genome …
people of various ethnicities. In this work, the analysis of the complete mtDNA genome …
[HTML][HTML] Facilitating accessible, rapid, and appropriate processing of ancient metagenomic data with AMDirT
…, KE Blevins, KG Daly, M Lopopolo… - …, 2023 - f1000research.com
Background: Access to sample-level metadata is important when selecting public metagenomic
sequencing datasets for reuse in new biological analyses. The Standards, Precautions, …
sequencing datasets for reuse in new biological analyses. The Standards, Precautions, …
RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus
Thymic epithelial cells (TEC) control the selection of a T cell repertoire reactive to pathogens
but tolerant of self. This process is known to involve the promiscuous expression of virtually …
but tolerant of self. This process is known to involve the promiscuous expression of virtually …
[HTML][HTML] Multiple Breath Washout for Early Assessment of Pulmonary Complications in Patients With Primary Antibody Deficiencies: An Observational Study in …
…, MC Russo, IM Borzani, F Carta, MA Lopopolo… - Frontiers in …, 2022 - frontiersin.org
Background. In Primary Antibody Deficiencies (PADs), pulmonary complications are the
main cause of morbidity, despite immunoglobulin substitutive therapy, antibiotic treatment of …
main cause of morbidity, despite immunoglobulin substitutive therapy, antibiotic treatment of …
The diagnostic chronic lymphocytic leukaemia genome by nanopore sequencing
…, A Timbs, B Stamatopoulos, R Clifford, M Lopopolo… - bioRxiv, 2019 - biorxiv.org
Chronic lymphocytic leukaemia (CLL) is characterised by considerable clinical and biological
heterogeneity, with specific recurrent genomic alterations, including TP53 mutations, …
heterogeneity, with specific recurrent genomic alterations, including TP53 mutations, …
[PDF][PDF] Rbfox contributes to a conservative program of self-antigen splicing in thymic epithelial cells
Thymic epithelial cells (TEC) guide selection of a T-cell repertoire that is reactive to pathogens
but tolerant to self. While this process is known to involve the promiscuous expression of …
but tolerant to self. While this process is known to involve the promiscuous expression of …