[HTML][HTML] Applications of bacterial degrons and degraders—Toward targeted protein degradation in bacteria

MA Izert, MM Klimecka, MW Górna - Frontiers in molecular …, 2021 - frontiersin.org
A repertoire of proteolysis-targeting signals known as degrons is a necessary component of
protein homeostasis in every living cell. In bacteria, degrons can be used in place of …

[HTML][HTML] A Uniform Benchmark for Testing SsrA-Derived Degrons in the Escherichia coli ClpXP Degradation Pathway

MM Klimecka, A Antosiewicz, MA Izert, PE Szybowska… - Molecules, 2021 - mdpi.com
The ssrA degron is commonly used in fusion proteins to control protein stability in bacteria or
as an interaction module. These applications often rely on the modular activities of the ssrA …

Towards Targeted Protein Degradation in Escherichia coli - depletion of the essential GroEL protein using CLIPPERs

MA Izert-Nowakowska, MM Klimecka, A Antosiewicz… - bioRxiv, 2024 - biorxiv.org
New, universal tools for targeted protein degradation in bacteria can help to accelerate
protein function studies and antimicrobial research. We have created a new method for …

A uniform benchmark for testing ssrA-derived degrons in the Escherichia coli ClpXP pathway

MM Klimecka, A Antosiewicz, MA Izert, PE Szybowska… - bioRxiv, 2021 - biorxiv.org
The ssrA degron is commonly used in fusion proteins to control protein stability in bacteria or
as an interaction module. These applications often rely on the modular activities of the ssrA …

Identification and functional characterization of the Arabidopsis Snf1‐related protein kinase SnRK2.4 phosphatidic acid‐binding domain

…, JM Rankenberg, D Kawa, M Klimecka… - Plant, cell & …, 2015 - Wiley Online Library
Phosphatidic acid ( PA ) is an important signalling lipid involved in various stress‐induced
signalling cascades. Two SnRK 2 protein kinases ( SnRK 2.4 and SnRK 2.10), previously …

Digitization of processes in manufacturing SMEs-value stream mapping and OEE analysis

D Klimecka-Tatar, M Ingaldi - Procedia Computer Science, 2022 - Elsevier
Revolution 4.0 and the resulting changes in process management have a very large impact
on the meaning and method of obtaining digital data. The Industry 4.0 principles are already …

Creation of the university curriculum in the field of Industry 4.0 with the use of modern teaching instruments-Polish case study

M Ingaldi, R Ulewicz, D Klimecka-Tatar - Procedia Computer Science, 2023 - Elsevier
The industrial revolution 4.0 causes the need for changes not only in terms of technology or
organization in the enterprises, but most of all requires new competences from employees. It …

Technological effects of european integration in the sustainable development context

ЛО Петкова, ДМ Паламарчук… - Proceedings of the 2nd …, 2018 - er.chdtu.edu.ua
The main purposes of the paper are assessment of technological changes of production
structure of the countries of the European Union, comparison of structural and technological …

Social Potential in The Conditions of Digitalization of Economy and Society: Evaluation and Opportunities for Development

S Kniaz, А Starukh, І Shevchuk… - … Association (IBIMA), 4 …, 2020 - elartu.tntu.edu.ua
The article is a study of social potential in the context of digitalization of the economy and
society and a consideration of its opportunities for development. The study establish that the …

Potential Management of The Enterprise from The Position of Functional Approach

S Kniaz, N Heorhiadi, L Sai, A Shchebel… - … Association (IBIMA), 4 …, 2020 - elartu.tntu.edu.ua
The potential of the enterprise is considered as a system of opportunities to achieve
development goals within the functions defined by the structure of the enterprise. In turn, the …