Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies
of heredity, development, metabolism, behavior, and human disease. The initial reference …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are the two most
common non-Hodgkin lymphomas (NHLs). Here we sequenced tumour and matched normal …

DNA single-strand breaks (SSBs) are among the most common lesions in the genome, arising
spontaneously and as intermediates of many DNA transactions. Nevertheless, in contrast …

Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous cancer composed of
at least 2 molecular subtypes that differ in gene expression and distribution of mutations. …

Genome sequences for most metazoans and plants are incomplete because of the presence
of repeated DNA in the heterochromatin. The heterochromatic regions of Drosophila …

Centromeres are the chromosomal loci at which spindle microtubules attach to mediate
chromosome segregation during mitosis and meiosis. In most eukaryotes, centromeres are …

Recent sequencing efforts have described the mutational landscape of the pediatric brain
tumor medulloblastoma. Although MLL2 is among the most frequent somatic single nucleotide …

Highly proliferative Lgr5+ stem cells maintain the intestinal epithelium and are thought to be
largely homogeneous. Although quiescent intestinal stem cell (ISC) populations have been …

The centromere is the DNA region of the eukaryotic chromosome that determines kinetochore
formation and sister chromatid cohesion. Centromeres interact with spindle microtubules …