… Maria Pino-Yanes, … Maria Pino-Yanes, … Citation: Oh SS, Galanter J, Thakur N, Pino-Yanes
M, Barcelo NE, White MJ, et al. (2015) Diversity in Clinical and Biomedical Research: A …

10.7554/eLife.20532.001 Populations are often divided categorically into distinct racial/ethnic
groups based on social rather than biological constructs. Genetic ancestry has been …

The African Diaspora in the Western Hemisphere represents one of the largest forced
migrations in history and had a profound impact on genetic diversity in modern populations. To …

Background Childhood asthma prevalence and morbidity varies among Latinos in the
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …

Allergic rhinitis is the most common clinical presentation of allergy, affecting 400 million
people worldwide, with increasing incidence in westernized countries 1 , 2 . To elucidate the …

Rationale: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide.
There are significant racial/ethnic differences in albuterol drug response. Objectives: To …

Rationale: Stress is associated with asthma morbidity in Puerto Ricans (PRs), who have
reduced bronchodilator response (BDR). Objectives: To examine whether stress and/or a gene …

Background Asthma is a common complex condition with clear racial and ethnic differences
in both prevalence and severity. Asthma consultation rates, mortality, and severe symptoms …

Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene
studies have suggested that genotype-by-sex interaction effects on asthma risk exist, but this …

Background The Gly-to-Arg substitution at the 16 position (rs1042713) in the β 2 -adrenoceptor
gene (ADRB2) is associated with enhanced downregulation and uncoupling of β 2 -…