What are white matter hyperintensities made of? Relevance to vascular cognitive impairment

JM Wardlaw, MC Valdés Hernández… - Journal of the …, 2015 - Am Heart Assoc
White matter hyperintensities (WMH) of presumed vascular origin, also referred to as leukoaraiosis,
are a very common finding on brain magnetic resonance imaging (MRI) or computed …

Identification of common variants associated with human hippocampal and intracranial volumes

…, C Smith, VM Steen, MC Valdés Hernández… - Nature …, 2012 - nature.com
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Blood pressure, internal carotid artery flow parameters, and age-related white matter hyperintensities

…, E Eadie, A Thomas, A Gow, MC Valdés Hernández… - …, 2014 - Am Heart Assoc
White matter hyperintensities (WMH) are associated with hypertension. We examined interactions
among blood pressure (BP), internal carotid artery (ICA) flow velocity parameters, and …

Circulating inflammatory markers are associated with magnetic resonance imaging-visible perivascular spaces but not directly with white matter hyperintensities

…, S Wiseman, Z Morris, MC Valdés-Hernández… - Stroke, 2014 - Am Heart Assoc
Background and Purpose— White matter hyperintensities (WMH) and perivascular spaces (PVS)
are features of small vessel disease, found jointly on MRI of older people. Inflammation …

[HTML][HTML] Colonización faríngea por bacterias potencialmente patógenas en niños sanos de una escuela primaria

…, O López Piñera, MJ Valdés Hernández - Revista Cubana de …, 2009 - scielo.sld.cu
FUENTES PAEZ, Yadira et al. Colonización faríngea por bacterias potencialmente patógenas
en niños sanos de una escuela primaria. Rev Cubana Med Trop [online]. 2009, vol. 61, n. …

Integrity of normal-appearing white matter: influence of age, visible lesion burden and hypertension in patients with small-vessel disease

…, FM Chappell, MC Valdés Hernández… - Journal of Cerebral …, 2017 - journals.sagepub.com
White matter hyperintensities accumulate with age and occur in patients with stroke, but their
pathogenesis is poorly understood. We measured multiple magnetic resonance imaging …

Blood–brain barrier permeability and long-term clinical and imaging outcomes in cerebral small vessel disease

JM Wardlaw, FN Doubal, M Valdes-Hernandez… - Stroke, 2013 - Am Heart Assoc
Background and Purpose— Increased blood–brain barrier (BBB) permeability occurs in
cerebral small vessel disease. It is not known if BBB changes predate progression of small …

Gan augmentation: Augmenting training data using generative adversarial networks

…, A Hammers, DA Dickie, MV Hernández… - arXiv preprint arXiv …, 2018 - arxiv.org
One of the biggest issues facing the use of machine learning in medical imaging is the lack
of availability of large, labelled datasets. The annotation of medical images is not only …

Rationale, design and methodology of the image analysis protocol for studies of patients with cerebral small vessel disease and mild stroke

MC Valdés Hernández, PA Armitage… - Brain and …, 2015 - Wiley Online Library
Rationale Cerebral small vessel disease ( SVD ) is common in ageing and patients with
dementia and stroke. Its manifestations on magnetic resonance imaging ( MRI ) include white …

Neuroprotective lifestyles and the aging brain: activity, atrophy, and white matter integrity

…, S Muñoz Maniega, MC Valdés Hernández… - Neurology, 2012 - AAN Enterprises
Objectives: Increased participation in leisure and physical activities may be cognitively protective.
Whether activity might protect the integrity of the brain's white matter, or reduce atrophy …