Recently approved by the FDA and European Medicines Agency, CAR-T cell therapy is a
new treatment option for B-cell malignancies. Currently, CAR-T cells are manufactured in …

ABDO, L. de M. et al. Improvement Car-T Cell therapy with ultra-fast protocoland il-15
membrane bound addition. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICALS, 7., …

In the last year, the first T-cell therapy modified to express the chimeric receptor antigen (CAR)
targeting the CD19 molecule, has been approved by the Food and Drug Administration (…

Recently, CAR-T cell immunotherapy was approved for the treatment of acute B cell leukemia
(B-ALL) and some lymphomas with promising results. However, the major drawbacks of …

Obesity is nowadays considered a pandemic which prevalence’s has been steadily
increasingly in western countries. It is a dynamic, complex, and multifactorial disease which …

Objective: This work sought to generate a 19BBz CAR-T cells with a short in vitro expansion
protocol based on the non-viral Sleeping Beauty (SB) transposon-based vector system. …

Objective: Based on the rationale of the NeoSamba protocol, the impact of neoadjuvant
treatment with combinations of FAC followed by taxane and the reverse order (taxane followed …

Objective: Establish a cancer immunotherapy model using NK cells loaded with CARs via a
trogocitosis-mediated CAR transfer. Methodology: NOD SCID mice were engrafted …

Objective: This work aims to evaluate the biosimilar and biobetters of rituximab developed in
Bio-Manguinhos regarding their ability to bind to the CD20 antigen and the in vitrobiological …

… 0027 MARIANA ALBUQUERQUE SALDANHA … LUISA SOARES VIEGAS DA ROCHA 0179
… 0473 LUANA OLIVEIRA DOS SANTOS DO NASCIMENTO 0250 LUCAS SOARES VIEGAS …