[HTML][HTML] Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro imaging genetics through meta …

…, F Assogna, N Banaj, P De Rossi, M Iorio… - Biological …, 2018 - Elsevier
Background The profile of cortical neuroanatomical abnormalities in schizophrenia is not
fully understood, despite hundreds of published structural brain imaging studies. This study …

[HTML][HTML] Atrophy of presubiculum and subiculum is the earliest hippocampal anatomical marker of Alzheimer's disease

GA Carlesimo, F Piras, MD Orfei, M Iorio… - Alzheimer's & Dementia …, 2015 - Elsevier
Background There is no consensus about which hippocampal subfields become atrophic
earliest in the course of Alzheimer's disease (AD). Methods Thirty AD patients, 41 mild …

[HTML][HTML] SARS-CoV-2 replicates in respiratory ex vivo organ cultures of domestic ruminant species

…, M Marcacci, N D'Alterio, V Curini, M Iorio… - Veterinary …, 2021 - Elsevier
There is strong evidence that severe acute respiratory syndrome 2 virus (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, originated from an …

[HTML][HTML] The molecular analysis of BRCA1 and BRCA2: Next-generation sequencing supersedes conventional approaches

…, F Starnone, M Nunziato, P Cantiello, M Iorio… - Clinica Chimica …, 2015 - Elsevier
Background Accurate and sensitive detection of BRCA1/2 germ-line mutations is crucial for
the clinical management of women affected by breast cancer, for prevention and, notably, …

Amygdala and hippocampus volumes are differently affected by childhood trauma in patients with bipolar disorders and healthy controls

D Janiri, G Sani, PD Rossi, F Piras, M Iorio… - Bipolar …, 2017 - Wiley Online Library
Objectives Volumetric studies on deep gray matter structures in bipolar disorder ( BP ) have
reported contrasting results. Childhood trauma, a relevant environmental stressor for BP , …

[HTML][HTML] White matter hyperintensities segmentation: a new semi-automated method

M Iorio, G Spalletta, C Chiapponi… - Frontiers in aging …, 2013 - frontiersin.org
White matter hyperintensities (WMH) are brain areas of increased signal on T2-weighted or
fluid-attenuated inverse recovery magnetic resonance imaging (MRI) scans. In this study we …

The superficial white matter in Alzheimer's disease

…, SH Joshi, F Piras, MD Orfei, M Iorio… - Human brain …, 2016 - Wiley Online Library
White matter abnormalities have been shown in the large deep fibers of Alzheimer's disease
patients. However, the late myelinating superficial white matter comprised of intracortical …

The embodied emotion in cerebellum: a neuroimaging study of alexithymia

…, L Petrosini, E Picerni, D Cutuli, M Iorio… - Brain Structure and …, 2015 - Springer
Neuroimaging studies have indicated that people with alexithymia show structural and
functional alterations in brain areas associated with emotional awareness, as amygdala, insula, …

Neuroanatomical correlates of awareness of illness in patients with amnestic mild cognitive impairment who will or will not convert to Alzheimer's disease

G Spalletta, F Piras, F Piras, G Sancesario, M Iorio… - Cortex, 2014 - Elsevier
Background Awareness of cognitive deficits may be reduced in mild cognitive impairment (MCI).
This may have a detrimental effect on illness course and may be a predictor of …

[HTML][HTML] The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice

…, N Massetti, V Castelli, M d'Aurora, M Punzi, M Iorio… - Scientific reports, 2018 - nature.com
Zinc (Zn 2+ ) is a pleiotropic modulator of the neuronal and brain activity. The disruption of
intraneuronal Zn 2+ levels triggers neurotoxic processes and affects neuronal functioning. In …