[HTML][HTML] Human recombinant soluble ACE2 in severe COVID-19

…, JH Aberle, W Hoepler, T Seitz, M Traugott… - The Lancet …, 2020 - thelancet.com
Angiotensin converting enzyme 2 (ACE2) is the crucial severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) receptor and protects multiple tissues, including the lung, from …

SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses

…, T Penz, D Barreca, I Fae, S Wenda, M Traugott… - Science …, 2021 - science.org
CD8 + T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus
control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8 + T cell …

[HTML][HTML] Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19

H Vietzen, A Zoufaly, M Traugott, J Aberle… - Genetics in …, 2021 - Elsevier
Purpose Host genetic variants may contribute to severity of COVID-19. NKG2C + NK cells
are potent antiviral effector cells, potentially limiting the extent of SARS-CoV-2 infections. …

Occupational challenges of healthcare workers during the COVID-19 pandemic: a qualitative study

M Jeleff, M Traugott, E Jirovsky-Platter, G Jordakieva… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To address structural determinants and healthcare workers’ (HCWs) physical,
mental, emotional and professional challenges of working during the COVID-19 pandemic. …

[HTML][HTML] Dynamics of CD4 T cell and antibody responses in COVID-19 patients with different disease severity

M Koblischke, MT Traugott, I Medits, FS Spitzer… - Frontiers in …, 2020 - frontiersin.org
Disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
ranges from mild illness to severe respiratory disease and death. In this study, we determined …

[HTML][HTML] Different neutralization profiles after primary SARS-CoV-2 Omicron BA. 1 and BA. 2 infections

…, JV Camp, E Höltl, SW Aberle, MT Traugott… - Frontiers in …, 2022 - frontiersin.org
Background and Methods The SARS-CoV-2 (severe acute respiratory syndrome coronavirus
2) Omicron (B.1.1.529) variant is the antigenically most distinct variant to date. As the …

[HTML][HTML] A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing

…, AD Straw, R Fritsche-Polanz, M Traugott… - Frontiers in Molecular …, 2022 - frontiersin.org
RT-qPCR-based diagnostic tests play important roles in combating virus-caused pandemics
such as Covid-19. However, their dependence on sophisticated equipment and the …

Performance of severe acute respiratory syndrome coronavirus 2 antibody assays in different stages of infection: comparison of commercial enzyme-linked …

M Traugott, SW Aberle, JH Aberle… - The Journal of …, 2020 - academic.oup.com
We comparatively assessed sensitivities and specificities of 4 commercial enzyme-linked
immunosorbent assays (ELISAs) and 2 rapid tests in 77 patients with polymerase chain …

Muscle involvement in SARS‐CoV‐2 infection

…, E Pawelka, S Omid, M Traugott… - European journal of …, 2021 - Wiley Online Library
Background and Purpose Since the outbreak of the severe acute respiratory syndrome
coronavirus‐2 (SARS‐CoV‐2) pandemic, several reports indicated neurological involvement in …

[HTML][HTML] Platelet phenotype analysis of COVID-19 patients reveals progressive changes in the activation of integrin αIIbβ3, F13A1, the SARS-CoV-2 Target EIF4A1 and …

…, J Santol, E Pawelka, MT Traugott… - Frontiers in …, 2021 - frontiersin.org
Background: The fatal consequences of an infection with severe acute respiratory syndrome
coronavirus 2 are not only caused by severe pneumonia, but also by thrombosis. Platelets …