Increased chondroitin sulfate proteoglycan (CSPG) expression in the vicinity of a spinal cord
injury (SCI) is a primary participant in axonal regeneration failure. However, the presence of …

Malignant gliomas are the most common tumors originating within the central nervous system
and account for over 15,000 deaths annually in the United States. The median survival for …

… Abbreviations: TCPS, tissue culture polystyrene Address all correspondence to: Mariano S.
Viapiano, … E-mail: viapiano.1@osu.edu 1This work was supported by grants from the National …

Glioblastoma multiforme (GBM), one of the deadliest forms of human cancer, is characterized
by its high infiltration capacity, partially regulated by the neural extracellular matrix (ECM). …

Malignant gliomas are highly invasive tumors with an almost invariably rapid and lethal outcome.
Surgery and chemoradiotherapy fail to remove resistant tumor cells that disperse within …

Chondroitin sulfate proteoglycans (CSPGs) present an inhibitory barrier to axonal growth
and plasticity after trauma to the central nervous system. These extracellular and membrane …

Glioblastoma (GBM) is the most aggressive form of brain cancer, with a dismal prognosis
and extremely low percentage of survivors. Novel therapies are in dire need to improve the …

The adult neural parenchyma contains a distinctive extracellular matrix that acts as a barrier
to cell and neurite motility. Nonneural tumors that metastasize to the central nervous system …

Emerging studies have revealed new roles for the neural extracellular matrix in neuropathologies.
The structure of this matrix is unusual and uniquely enriched in chondroitin sulfate …

Real-time, continuous monitoring of local oxygen contents at the cellular level is desirable
both for the study of cancer cell biology and in tissue engineering. In this paper, we report the …