In vitro cultured neuronal networks coupled to microelectrode arrays (MEAs) constitute a
valuable experimental model for studying changes in the neuronal dynamics at different stages …

This paper presents a chip-based electrophysiological platform enabling the study of micro-
and macro-circuitry in in-vitro neuronal preparations. The approach is based on a 64 × 64 …

Despite the extensive use of in-vitro models for neuroscientific investigations and notwithstanding
the growing field of network electrophysiology, all studies on cultured cells devoted to …

Synapsins (Syns) are synaptic vesicle (SV) phosphoproteins that play a role in synaptic
transmission and plasticity. Mutation of the SYN1 gene results in an epileptic phenotype in …

It is widely recognized that extracellular vesicles subserve non-classical signal transmission
in the central nervous system. Here we assess if the astrocyte processes, that are …

In vitro neuronal cultures exhibit spontaneous electrophysiological activity that can be
modulated by chemical stimulation and can be monitored over time by using Micro-Electrode …

Brain-machine interfaces (BMI) were born to control “actions from thoughts” in order to recover
motor capability of patients with impaired functional connectivity between the central and …

Co-cultures containing dissociated cortical and thalamic cells may provide a unique model
for understanding the pathophysiology in the respective neuronal sub-circuitry. In addition, …

We used electrophysiological signals recorded by CMOS Micro Electrode Arrays (MEAs) at
high spatial resolution to estimate the functional-effective connectivity of sparse hippocampal …

Recent advances in bioelectronics and neural engineering allowed the development of brain
machine interfaces and neuroprostheses, capable of facilitating or recovering functionality …