User profiles for Marie Pronot
 | Marie PronotIPMC - Université Côte d'Azur Verified email at ipmc.cnrs.fr Cited by 163 |
[HTML][HTML] Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation
Fragile X syndrome (FXS) is the most frequent inherited cause of intellectual disability and
the best-studied monogenic cause of autism. FXS results from the functional absence of the …
the best-studied monogenic cause of autism. FXS results from the functional absence of the …
[HTML][HTML] Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
…, G Poupon, S Schiavi, V Buzzelli, M Pronot… - Nature …, 2021 - nature.com
Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the
best-described monogenic cause of autism. CGG-repeat expansion in the FMR1 gene …
best-described monogenic cause of autism. CGG-repeat expansion in the FMR1 gene …
[HTML][HTML] A synaptomic analysis reveals dopamine hub synapses in the mouse striatum
Dopamine transmission is involved in reward processing and motor control, and its
impairment plays a central role in numerous neurological disorders. Despite its strong …
impairment plays a central role in numerous neurological disorders. Despite its strong …
[PDF][PDF] Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis
EM Blumrich, JC Nicholson-Fish, M Pronot… - Cell Reports, 2023 - cell.com
Phosphatidylinositol 4-kinase IIα (PI4KIIα) generates essential phospholipids and is a cargo
for endosomal adaptor proteins. Activity-dependent bulk endocytosis (ADBE) is the …
for endosomal adaptor proteins. Activity-dependent bulk endocytosis (ADBE) is the …
[HTML][HTML] Molecular Organization and Regulation of the Mammalian Synapse by the Post-Translational Modification SUMOylation
Neurotransmission occurs within highly specialized compartments forming the active synapse
where the complex organization and dynamics of the interactions are tightly orchestrated …
where the complex organization and dynamics of the interactions are tightly orchestrated …
[HTML][HTML] Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy
…, A Gajbhiye, EC Davenport, M Pronot… - Nature …, 2023 - nature.com
Dynamin-1 is a large GTPase with an obligatory role in synaptic vesicle endocytosis at
mammalian nerve terminals. Heterozygous missense mutations in the dynamin-1 gene (DNM1) …
mammalian nerve terminals. Heterozygous missense mutations in the dynamin-1 gene (DNM1) …
The synaptic balance between sumoylation and desumoylation is maintained by the activation of metabotropic mGlu5 receptors
Sumoylation is a reversible post-translational modification essential to the modulation of
neuronal function, including neurotransmitter release and synaptic plasticity. A tightly regulated …
neuronal function, including neurotransmitter release and synaptic plasticity. A tightly regulated …
[HTML][HTML] Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
SUMOylation is a post-translational modification essential to cell homeostasis. A tightly
controlled equilibrium between SUMOylation and deSUMOylation processes is also critical to the …
controlled equilibrium between SUMOylation and deSUMOylation processes is also critical to the …
[HTML][HTML] Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP
The Fragile X-Syndrome (FXS) represents the most common inherited form of intellectual
disability and the first monogenic cause of Autism Spectrum Disorders. In most of cases, this …
disability and the first monogenic cause of Autism Spectrum Disorders. In most of cases, this …
[HTML][HTML] Proteomic identification of an endogenous synaptic SUMOylome in the developing rat brain
M Pronot, F Kieffer, AS Gay, D Debayle… - Frontiers in Molecular …, 2021 - frontiersin.org
Synapses are highly specialized structures that interconnect neurons to form functional
networks dedicated to neuronal communication. During brain development, synapses undergo …
networks dedicated to neuronal communication. During brain development, synapses undergo …