The first report of trans-acting RNA-based regulation in bacterial cells dates back to 1984.
Subsequent studies in diverse bacteria unraveled shared properties of trans-acting small …

During ribosomal and transfer RNA maturation, external transcribed spacer (ETS) and internal
transcribed spacer (ITS) sequences are excised and, as non-functional by-products, are …

RNA binding proteins (RBPs) are ubiquitously found in all kingdoms of life. They are involved
in a plethora of regulatory events, ranging from direct regulation of gene expression to …

In the last few decades, small regulatory RNA (sRNA) molecules emerged as key regulators
in every kingdom of life. Resolving the full targetome of sRNAs has however remained a …

The 87 nucleotide long DsrA s RNA has been mostly studied for its translational activation of
the transcriptional regulator RpoS . However, it also represses hns m RNA , which encodes …

RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In
bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator. Using …

Prokaryotic organisms often react instantly to environmental variations to ensure their survival.
They can achieve this by rapidly and specifically modulating translation, the critical step of …

For over half a century, tRNAs have been exclusively known as decoders of genomic information.
However, recent reports evidenced that tRNA transcripts are also bearers of functional …

Small regulatory RNAs (sRNAs) are ubiquitous regulatory molecules expressed in living cells.
In prokaryotes, sRNAs usually bind to target mRNAs to either promote their degradation or …

The cyanobacterium Synechocystis relies on iron to perform oxygenic photosynthesis. This
makes Synechocystis particularly sensitive to iron starvation. A new study shows that the …