Signalling by means of toll-like receptors (TLRs) is essential for the development of innate
and adaptive immune responses 1 , 2 , 3 . UNC93B1, essential for signalling of TLR3, TLR7 …

As the technological hurdles are overcome and optogenetic techniques advance to have
more control over neurons, therapies based on these approaches will begin to emerge in the …

The importance of the gut microbiota in host health is now well established, but the underlying
mechanisms remain poorly understood. Among the animal models used to investigate …

Human neutrophils have been shown recently to express both the beta and the gamma chains
of the interleukin-2 receptor (IL-2R). IL-15, a cytokine that has recently been cloned and …

l-Lactate is increasingly appreciated as a key metabolite and signaling molecule in mammals.
However, investigations of the inter- and intra-cellular dynamics of l-lactate are currently …

Endoglin is predominantly expressed on endothelium and is mutated in hereditary hemorrhagic
telangiectasia (HHT) type 1 (HHT1). We report the analysis of endoglin in tissues of a …

l-Lactate, traditionally considered a metabolic waste product, is increasingly recognized as
an important intercellular energy currency in mammals. To enable investigations of the …

In this study, we examine the role of the putative cargo receptor B cell-associated protein (Bap)
29/31 in the export of MHC class I molecules out of the endoplasmic reticulum (ER). We …

Disinhibition during early stages of Alzheimer's disease is postulated to cause network
dysfunction and hyperexcitability leading to cognitive deficits. However, the underlying molecular …

The Frontiers in Neurophotonics Symposium is a biennial event that brings together
neurobiologists and physicists/engineers who share interest in the development of leading-edge …