Spatially controlled polymerization of actin is at the origin of cell motility and is responsible
for the formation of cellular protrusions like lamellipodia. The pathogens Listeria …

To migrate, a cell first extends protrusions such as lamellipodia and filopodia, forms adhesions,
and finally retracts its tail. The actin cytoskeleton plays a major role in this process. The …

Actin polymerization is essential for cell locomotion and is thought to generate the force
responsible for cellular protrusions. The Arp2/3 complex is required to stimulate actin assembly …

F-actin is the major component of muscle thin filaments and, more generally, of the
microfilaments of the dynamic, multifunctional cytoskeletal systems of nonmuscle eukaryotic cells. …

Mycolactone is a diffusible lipid secreted by the human pathogen Mycobacterium ulcerans,
which induces the formation of open skin lesions referred to as Buruli ulcers. Here, we show …

Actin polymerization plays a major role in cell movement. The controls of actin sequestration/desequestration
and of filament turnover are two important features of cell motility. Actin …

Actin-binding proteins of the actin depolymerizing factor (ADF)/cofilin family are thought to
control actin-based motile processes. ADF1 from Arabidopsis thaliana appears to be a good …

The role of profilin in the regulation of actin assembly has been reexamined. The affinity of
profilin for ATP-actin appears lo-fold higher than previously thought. In the presence of ATP, …

Single actin filaments undergoing brownian movement in two dimensions were observed at
20 C in fluorescence optical video microscopy. The persistence length (L p ) was derived …

Motile and morphogenetic cellular processes are driven by site-directed assembly of actin
filaments. Formins, proteins characterized by formin homology domains FH1 and FH2, are …