User profiles for Marie-Isabelle Garcia

Marie Isabelle Garcia

ULB
Verified email at ulb.ac.be
Cited by 1655

[PDF][PDF] Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium

…, D Monteyne, D Pérez-Morga, G Vassart, MI Garcia - Cell reports, 2013 - cell.com
Immortal spheroids were generated from fetal mouse intestine using the culture system
initially developed to culture organoids from adult intestinal epithelium. Spheroid proportion …

[HTML][HTML] LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

MI Garcia, M Ghiani, A Lefort, F Libert, S Strollo… - Developmental …, 2009 - Elsevier
The orphan Leucine-rich repeat G protein-coupled receptor 5 (LGR5/GPR49), a target of Wnt
signaling, is a marker of adult intestinal stem cells (SC). However, neither its function in the …

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo

…, A Lefort, F Libert, S Strollo, G Vassart, MI Garcia - EMBO …, 2011 - embopress.org
Gene inactivation of the orphan G protein‐coupled receptor LGR4, a paralogue of the
epithelial‐stem‐cell marker LGR5, results in a 50% decrease in epithelial cell proliferation and an …

Characterization of AfaE Adhesins Produced by Extraintestinal and Intestinal Human Escherichia coliIsolates: PCR Assays for Detection of Afa Adhesins That Do or …

…, A Andremont, P Gounon, MI Garcia - Journal of Clinical …, 2001 - Am Soc Microbiol
Operons of the afa family are expressed by pathogenicEscherichia coli strains associated
with intestinal and extraintestinal infections in humans and animals. The recently …

Adhesion to and invasion of HeLa cells by pathogenic Escherichia coli carrying the afa-3 gene cluster are mediated by the AfaE and AfaD proteins, respectively

M Jouve, MI Garcia, P Courcoux, A Labigne… - Infection and …, 1997 - Am Soc Microbiol
The afa-3 gene cluster, expressed by uropathogenic and diarrhea-associated Escherichia
coli strains, determines the formation of an afimbrial adhesive sheath composed of the AfaD …

Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland

…, J Chappell, P Matthys, MI Garcia… - Proceedings of the …, 2021 - National Acad Sciences
Stem cells in the adult pituitary are quiescent yet show acute activation upon tissue injury.
The molecular mechanisms underlying this reaction are completely unknown. We applied …

α4β1 integrin acts as a cell receptor for murine polyomavirus at the postattachment level

…, L Belloni, O Sthandier, P Amati, MI Garcia - Journal of …, 2003 - Am Soc Microbiol
The initial interaction of murine polyomavirus (Py) with host cells occurs through direct binding
of the major capsid protein VP1 with cell membrane molecules containing terminal sialic …

[HTML][HTML] LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

…, G Vassart, A Cariboni, M Bonomi, MI Garcia… - JCI insight, 2020 - ncbi.nlm.nih.gov
The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing
hormone (GnRH) secretion. In turn, GnRH secretion upsurge depends on the development of a …

Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage

…, A Lefort, F Libert, G Vassart, MI Garcia - …, 2016 - journals.biologists.com
Mouse fetal intestinal progenitors lining the epithelium prior to villogenesis grow as spheroids
when cultured ex vivo and express the transmembrane glycoprotein Trop2 as a marker. …

Characterization of plasmid-borne afa-3 gene clusters encoding afimbrial adhesins expressed by Escherichia coli strains associated with intestinal or urinary tract …

C Le Bouguenec, MI Garcia, V Ouin… - Infection and …, 1993 - Am Soc Microbiol
The afa gene clusters encode afimbrial adhesins (AFA) that are expressed by uropathogenic
and diarrhea-associated Escherichia coli strains and belong to a family of hemagglutinins …