Research in the basic biology of ageing is increasingly identifying mechanisms and modifiers
of ageing in short-lived organisms such as worms and mice. The ultimate goal of such …

Weather-related disasters are increasing in frequency and severity, leaving survivors to
cope with ensuing mental, financial, and physical hardships. This adversity can exacerbate …

Climate change is increasing the frequency and intensity of weather-related disasters such
as hurricanes, wildfires, floods, and droughts. Understanding resilience and vulnerability to …

Across mammals, increased body size is positively associated with lifespan. However, within
species, this relationship is inverted. This is well illustrated in dogs (Canis familiaris), where …

Monitoring genetic diversity in wild populations is a central goal of ecological and evolutionary
genetics and is critical for conservation biology. However, genetic studies of nonmodel …

Social adversity can increase the age-associated risk of disease and death, yet the
biological mechanisms that link social adversities to aging remain poorly understood. Long-term …

Increasing age is associated with dysregulated immune function and increased
inflammation—patterns that are also observed in individuals exposed to chronic social adversity. Yet …

Identifying biomarkers of age-related changes in immune system functioning that can be
measured non-invasively is a significant step in progressing research on immunosenescence …

Nonhuman primates (NHPs) are vital translational research models due to their high genetic,
physiological, and anatomical homology with humans. The “golden” rhesus macaque (…

Aging results in declines in immune function and increases in inflammation, which underlie
many age-related diseases. These immunosenescent signatures are similar to those seen in …