Lamin B2 follows lamin A/C-mediated nuclear mechanics and cancer cell invasion efficacy

M Vortmeyer-Krause, M Lindert, J Riet, V Boekhorst… - BioRxiv, 2020 - biorxiv.org
Interstitial tumor cell invasion depends upon complex mechanochemical adaptation of both
cell body and the rigid nucleus in response to extracellular tissue topologies. Nuclear …

An epigenetic small molecule screen to target abnormal nuclear morphology in human cells

KR Atanasova, S Chakraborty… - Molecular Biology of …, 2022 - Am Soc Cell Biol
Irregular nuclear shapes are a hallmark of human cancers. Recent studies suggest that
alterations to chromatin regulators may cause irregular nuclear morphologies. Here we screened …

Components and mechanisms of nuclear mechanotransduction

P Niethammer - Annual review of cell and developmental …, 2021 - annualreviews.org
The cell nucleus is best known as the container of the genome. Its envelope provides a barrier
for passive macromolecule diffusion, which enhances the control of gene expression. As …