[PDF][PDF] Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans
Emerging evidence indicates a central role for the microbiome in immunity. However, causal
evidence in humans is sparse. Here, we administered broad-spectrum antibiotics to healthy …
evidence in humans is sparse. Here, we administered broad-spectrum antibiotics to healthy …
Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes
Vaccine adjuvants such as alum and the oil-in-water emulsion MF59 are used to enhance
immune responses towards pure soluble antigens, but their mechanism of action is still largely …
immune responses towards pure soluble antigens, but their mechanism of action is still largely …
[PDF][PDF] The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination
…, HT Maecker, R van der Most, P Cheung, M Cortese… - Cell, 2021 - cell.com
Emerging evidence indicates a fundamental role for the epigenome in immunity. Here, we
mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination in …
mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination in …
[HTML][HTML] Modeling human adaptive immune responses with tonsil organoids
…, KM Blaine, KD Meister, IN Ahmad, M Cortese… - Nature medicine, 2021 - nature.com
Most of what we know about adaptive immunity has come from inbred mouse studies, using
methods that are often difficult or impossible to confirm in humans. In addition, vaccine …
methods that are often difficult or impossible to confirm in humans. In addition, vaccine …
A light-weight active orthosis for hip movement assistance
In the last decades, wearable powered orthoses have been developed with the aim of
augmenting or assisting motor activities. In particular, among many applications, wearable …
augmenting or assisting motor activities. In particular, among many applications, wearable …
Hybrid EEG/EOG-based brain/neural hand exoskeleton restores fully independent daily living activities after quadriplegia
Direct brain control of advanced robotic systems promises substantial improvements in health
care, for example, to restore intuitive control of hand movements required for activities of …
care, for example, to restore intuitive control of hand movements required for activities of …
A powered finger–thumb wearable hand exoskeleton with self-aligning joint axes
In recent years, the robotic research area has become extremely prolific in terms of wearable
active exoskeletons for human body motion assistance, with the presentation of many novel …
active exoskeletons for human body motion assistance, with the presentation of many novel …
Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood
The dynamics and molecular mechanisms underlying vaccine immunity in early childhood
remain poorly understood. Here we applied systems approaches to investigate the innate and …
remain poorly understood. Here we applied systems approaches to investigate the innate and …
MF59 and Pam3CSK4 boost adaptive responses to influenza subunit vaccine through an IFN type I-independent mechanism of action
The innate immune pathways induced by adjuvants required to increase adaptive responses
to influenza subunit vaccines are not well characterized. We profiled different TLR-…
to influenza subunit vaccines are not well characterized. We profiled different TLR-…
[HTML][HTML] An ecologically-controlled exoskeleton can improve balance recovery after slippage
The evolution to bipedalism forced humans to develop suitable strategies for dynamically
controlling their balance, ensuring stability, and preventing falling. The natural aging process …
controlling their balance, ensuring stability, and preventing falling. The natural aging process …