The determination of a representative set of protein structures is a chief aim in structural
genomics. Solid-state NMR may have a crucial role in structural investigations of those proteins …

In many γ‐proteobacteria, the conserved GacS/GacA (BarA/UvrY) two‐component system
positively controls the expression of one to five genes specifying small RNAs (sRNAs) that are …

The chemical shift difference (δ[ 13 C β ] − δ[ 13 C γ ]) is a reference-independent indicator
of the Xaa-Pro peptide bond conformation. Based on a statistical analysis of the 13 C …

Proteins of the RsmA/CsrA family are global translational regulators in many bacterial
species. We have determined the solution structure of a complex formed between the RsmE …

MicroRNA and protein sequestration by non-coding RNAs (ncRNAs) has recently generated
much interest. In the bacterial Csr/Rsm system, which is considered to be the most general …

Starch contains phosphate covalently bound to the C6-position (70 to 80% of total bound
phosphate) and the C3-position (20 to 30%) of the glucosyl residues of the amylopectin fraction…

δ-secretase, also known as asparagine endopeptidase (AEP) or legumain, is a lysosomal
cysteine protease that cleaves both amyloid precursor protein (APP) and tau, mediating the …

OBJECTIVE: The significant role of direct contact between hematopoietic progenitor cells (HPC)
and the cellular microenvironment for maintaining “stemness” has been demonstrated. …

Full article: A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor
mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a …

OBJECTIVE: Animal models have provided evidence for the existence of leukemia stem
cells (LSC). However, prospective isolation of human LSC from patients with acute myeloid …