Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the …

…, AFH Stalenhoef, E Stroes, MR Taskinen… - European heart …, 2014 - academic.oup.com
Aims Homozygous familial hypercholesterolaemia (HoFH) is a rare life-threatening condition
characterized by markedly elevated circulating levels of low-density lipoprotein cholesterol (…

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

…, ES Stroes, MR Taskinen… - European heart …, 2015 - academic.oup.com
Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart
disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated …

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and …

…, G De Backer, I Graham, MR Taskinen… - European heart …, 2011 - academic.oup.com
Surveys and registries are needed to verify that real-life daily practice is in keeping with
what is recommended in the guidelines, thus completing the loop between clinical research, …

Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome: the …

…, C Pardy, M d'Emden, D Tse, MR Taskinen… - Diabetes …, 2009 - Am Diabetes Assoc
OBJECTIVE—We explored whether cardiovascular disease (CVD) risk and the effects of
fenofibrate differed in subjects with and without metabolic syndrome and according to various …

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

…, DJ Richter, MS Sabatine, MR Taskinen… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals’ websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Cardiovascular morbidity and mortality associated with the metabolic syndrome

…, B Forsen, K Lahti, M Nissen, MR Taskinen… - Diabetes …, 2001 - Am Diabetes Assoc
OBJECTIVE—To estimate the prevalence of and the cardiovascular risk associated with the
metabolic syndrome using the new definition proposed by the World Health Organization (…

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial.

…, P Barter, J Best, R Scott, MR Taskinen… - Lancet (London …, 2005 - europepmc.org
Background Patients with type 2 diabetes mellitus are at increased risk of cardiovascular
disease, partly owing to dyslipidaemia, which can be amenable to fibrate therapy. We designed …

Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the …

…, B Van De Sluis, MR Taskinen… - European heart …, 2017 - academic.oup.com
Aims To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs)
cause atherosclerotic cardiovascular disease (ASCVD). Methods and results We assessed …

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus …

…, AFH Stalenhoef, E Stroes, MR Taskinen… - European heart …, 2013 - academic.oup.com
Aims The first aim was to critically evaluate the extent to which familial hypercholesterolaemia
(FH) is underdiagnosed and undertreated. The second aim was to provide guidance for …

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

…, L Råstam, EK Speliotes, MR Taskinen… - Science, 2007 - science.org
New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight
into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (…