User profiles for Mark A. Schembri

Mark Andrew Schembri

Professor of Microbiology, Institute for Molecular Bioscience (IMB), University of Queensland
Verified email at uq.edu.au
Cited by 24813

Antimicrobial resistance in ESKAPE pathogens

…, TJ Kidd, PNA Harris, MA Schembri… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE ( Enterococcus faecium , Staphylococcus aureus , Klebsiella
pneumoniae , Acinetobacter baumannii , Pseudomonas aeruginosa , and Enterobacter …

[HTML][HTML] Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

…, N Bagge, N Kumar, MA Schembri… - The EMBO …, 2003 - embopress.org
Traditional treatment of infectious diseases is based on compounds that kill or inhibit growth
of bacteria. A major concern with this approach is the frequent development of resistance to …

Global gene expression in Escherichia coli biofilms

MA Schembri, K Kjærgaard, P Klemm - Molecular microbiology, 2003 - Wiley Online Library
It is now apparent that microorganisms undergo significant changes during the transition from
planktonic to biofilm growth. These changes result in phenotypic adaptations that allow the …

Global dissemination of a multidrug resistant Escherichia coli clone

…, TR Walsh, MA Schembri… - Proceedings of the …, 2014 - National Acad Sciences
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR)
clone responsible for a high proportion of urinary tract and bloodstream infections. …

Bacterial adhesins: function and structure

P Klemm, MA Schembri - International journal of medical microbiology, 2000 - Elsevier
Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens.
The fundamental processes that determine bacterial attachment to host tissue surfaces …

Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

…, KJ Mansfield, KH Moore, MA Schembri… - FEMS microbiology …, 2012 - academic.oup.com
Bladder infections affect millions of people yearly, and recurrent symptomatic infections (cystitis)
are very common. The rapid increase in infections caused by multidrug-resistant …

Development and maturation of Escherichia coli K‐12 biofilms

A Reisner, JAJ Haagensen, MA Schembri… - Molecular …, 2003 - Wiley Online Library
The development and maturation of E. coli biofilms in flow‐chambers was investigated. We
found that the presence of transfer constitutive IncF plasmids induced biofilm development …

Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin

…, KA Krogfelt, C Struve, MA Schembri… - Proceedings of the …, 1998 - National Acad Sciences
Conventional wisdom regarding mechanisms of bacterial pathogenesis holds that pathogens
arise by external acquisition of distinct virulence factors, whereas determinants shared by …

The emerging threat of multidrug-resistant Gram-negative bacteria in urology

…, MJ Roberts, PA Tambyah, MA Schembri… - Nature Reviews …, 2015 - nature.com
Antibiotic resistance in Gram-negative uropathogens is a major global concern. Worldwide,
the prevalence of Enterobacteriaceae that produce extended-spectrum β-lactamase or …

Antidepressants can induce mutation and enhance persistence toward multiple antibiotics

…, Z Yuan, J Engelstädter, MA Schembri… - Proceedings of the …, 2023 - National Acad Sciences
Antibiotic resistance is an urgent threat to global health. Antidepressants are consumed in
large quantities, with a similar pharmaceutical market share (4.8%) to antibiotics (5%). While …