User profiles for Mark Howison

Mark Howison

Sr. Director of Research and Technology, Research Improving People's Lives
Verified email at ripl.org
Cited by 2345

[PDF][PDF] Comparative transmissibility of SARS-CoV-2 variants delta and alpha in New England, USA

…, E King, RC Huard, V Novitsky, M Howison… - Cell Reports …, 2022 - cell.com
The SARS-CoV-2 Delta variant rose to dominance in mid-2021, likely propelled by an
estimated 40%–80% increased transmissibility over Alpha. To investigate if this ostensible …

[HTML][HTML] Phylogenomic analyses support traditional relationships within Cnidaria

F Zapata, FE Goetz, SA Smith, M Howison, S Siebert… - PloS one, 2015 - journals.plos.org
Cnidaria, the sister group to Bilateria, is a highly diverse group of animals in terms of morphology,
lifecycles, ecology, and development. How this diversity originated and evolved is not …

Phylogenomic analyses of deep gastropod relationships reject Orthogastropoda

F Zapata, NG Wilson, M Howison… - … of the Royal …, 2014 - royalsocietypublishing.org
Gastropods are a highly diverse clade of molluscs that includes many familiar animals, such
as limpets, snails, slugs and sea slugs. It is one of the most abundant groups of animals in …

The Mathematical Imagery Trainer: from embodied interaction to conceptual learning

M Howison, D Trninic, D Reinholz… - Proceedings of the …, 2011 - dl.acm.org
We introduce an embodied-interaction instructional design, the Mathematical Imagery
Trainer (MIT), for helping young students develop grounded understanding of proportional …

[HTML][HTML] Agalma: an automated phylogenomics workflow

CW Dunn, M Howison, F Zapata - BMC bioinformatics, 2013 - Springer
Background In the past decade, transcriptome data have become an important component
of many phylogenetic studies. They are a cost-effective source of protein-coding gene …

Extreme scaling of production visualization software on diverse architectures

…, S Ahern, B Whitlock, M Howison… - IEEE Computer …, 2010 - ieeexplore.ieee.org
A series of experiments studied how visualization software scales to massive data sets.
Although several paradigms exist for processing large data, the experiments focused on pure …

Parallel I/O, analysis, and visualization of a trillion particle simulation

…, V Roytershteyn, EW Bethel, M Howison… - SC'12: Proceedings …, 2012 - ieeexplore.ieee.org
Petascale plasma physics simulations have recently entered the regime of simulating trillions
of particles. These unprecedented simulations generate massive amounts of data, posing …

Parallel index and query for large scale data analysis

J Chou, M Howison, B Austin, K Wu, J Qiang… - Proceedings of 2011 …, 2011 - dl.acm.org
Modern scientific datasets present numerous data management and analysis challenges.
State-of-the-art index and query technologies are critical for facilitating interactive exploration …

Tuning hdf5 for lustre file systems

M Howison - 2010 - escholarship.org
HDF5 is a cross-platform parallel I/O library that is used by a wide variety of HPC applications
for the flexibility of its hierarchical object-database representation of scientific data. We …

[HTML][HTML] Performance comparison of next generation sequencing analysis pipelines for HIV-1 drug resistance testing

…, CJ Brumme, E Enns, M Casadellà, M Howison… - Scientific Reports, 2020 - nature.com
Next generation sequencing (NGS) is a trending new standard for genotypic HIV-1 drug
resistance (HIVDR) testing. Many NGS HIVDR data analysis pipelines have been independently …