User profiles for Mark Roosjen

Mark Roosjen

Wageningen University
Verified email at wur.nl
Cited by 557

Cell surface and intracellular auxin signalling for H+ fluxes in root growth

L Li, I Verstraeten, M Roosjen, K Takahashi… - Nature, 2021 - nature.com
Growth regulation tailors development in plants to their environment. A prominent example
of this is the response to gravity, in which shoots bend up and roots bend down 1 . This …

ABP1–TMK auxin perception for global phosphorylation and auxin canalization

…, E Mazur, A Monzer, L Rodriguez, M Roosjen… - Nature, 2022 - nature.com
The phytohormone auxin triggers transcriptional reprogramming through a well-characterized
perception machinery in the nucleus. By contrast, mechanisms that underlie fast effects of …

Highly specific protein identification by immunoprecipitation–mass spectrometry using antifouling microbeads

E Van Andel, M Roosjen… - … Applied Materials & …, 2022 - ACS Publications
A common method to study protein complexes is immunoprecipitation (IP), followed by mass
spectrometry (thus labeled: IP-MS). IP-MS has been shown to be a powerful tool to identify …

Auxin response factors: output control in auxin biology

M Roosjen, S Paque, D Weijers - Journal of experimental botany, 2018 - academic.oup.com
The phytohormone auxin is involved in almost all developmental processes in land plants.
Most, if not all, of these processes are mediated by changes in gene expression. Auxin acts …

A RAF-like kinase mediates a deeply conserved, ultra-rapid auxin response

A Kuhn, M Roosjen, S Mutte, SM Dubey, PC Carrasco… - bioRxiv, 2022 - biorxiv.org
The plant signaling molecule auxin triggers both fast and slow cellular responses across the
plant kingdom, including both land plants and algae. A nuclear response pathway mediates …

Click-MS: tagless protein enrichment using bioorthogonal chemistry for quantitative proteomics

AH Smits, A Borrmann, M Roosjen… - ACS chemical …, 2016 - ACS Publications
Epitope-tagging is an effective tool to facilitate protein enrichment from crude cell extracts.
Traditionally, N- or C-terminal fused tags are employed, which, however, can perturb protein …

Specification and regulation of vascular tissue identity in the Arabidopsis embryo

ME Smit, CI Llavata-Peris, M Roosjen… - …, 2020 - journals.biologists.com
ABSTRACT Development of plant vascular tissues involves tissue identity specification,
growth, pattern formation and cell-type differentiation. Although later developmental steps are …

Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β‐like globin genes

M Roosjen, B McColl, B Kao, LJ Gearing… - The FASEB …, 2014 - Wiley Online Library
The clinical symptoms of hemoglobin disorders such as β‐thalassemia and sickle cell
anemia are significantly ameliorated by the persistent expression of γ‐globin after birth. This …

Cooperative action of separate interaction domains promotes high-affinity DNA binding of Arabidopsis thaliana ARF transcription factors

M Fontana, M Roosjen… - Proceedings of the …, 2023 - National Acad Sciences
The signaling molecule auxin coordinates many growth and development processes in plants,
mainly through modulating gene expression. Transcriptional response is mediated by the …

[PDF][PDF] RAF-like protein kinases mediate a deeply conserved, rapid auxin response

A Kuhn, M Roosjen, S Mutte, SM Dubey, VPC Carrasco… - Cell, 2024 - cell.com
The plant-signaling molecule auxin triggers fast and slow cellular responses across land
plants and algae. The nuclear auxin pathway mediates gene expression and controls growth …