The covalent marking of proteins by methyl group addition to arginine residues can promote
their recognition by binding partners or can modulate their biological activity. A small family …

Arginine methylation is now coming out of the shadows of protein phosphorylation and
entering the mainstream, largely due to the identification of the family of enzymes that lay down …

There are nine protein arginine methyltransferases (PRMTs) encoded in mammalian
genomes, the protein products of which catalyse three types of arginine methylation — …

p53, the tumour suppressor and transcriptional activator, is regulated by numerous post-translational
modifications, including lysine methylation 1 , 2 . Histone lysine methylation has …

The gene for fibroblast growth factor receptor-2 (FGFR2) encodes two splice variants designated
here as keratinocyte growth factor (KGFR) and bek. Their ligand-binding specificity is …

Arginine methylation is a common posttranslational modification (PTM). This type of PTM
occurs on both nuclear and cytoplasmic proteins, and is particularly abundant on shuttling …

The post‐translational modification of histones regulates many cellular processes, including
transcription, replication and DNA repair. A large number of combinations of post‐…

Biological responses to histone methylation critically depend on the faithful readout and
transduction of the methyl-lysine signal by “effector” proteins, yet our understanding of methyl-…

Protein methylation is a common posttranslational modification that mostly occurs on arginine
and lysine residues. Arginine methylation has been reported to regulate RNA processing, …

Arginine methylation is a prevalent post-translational modification found on both nuclear
and cytoplasmic proteins. The methylation of arginine residues is catalyzed by the protein …