BACKGROUND & AIMS: Mechanisms leading to non-alcoholic steatohepatitis (NASH) have
remained unclear, and non-invasive diagnosis of NASH is challenging. In this study, we …

We determined whether the polymorphism of the gene encoding adiponectin contributes to
susceptibility to preeclampsia. The study involved 133 Finnish women with preeclampsia …

Insulin resistance and hyperinsulinemia are major predictors of NIDDM. Since several
studies have demonstrated that heredity plays a significant role in the development of insulin …

… Markku Laakso … Lars Rydén, Eberhard Standl, Małgorzata Bartnik, Greet Van den
Berghe, John Betteridge, Menko-Jan de Boer, Francesco Cosentino, Bengt Jönsson …

Background— Catheter-based intracoronary vascular endothelial growth factor (VEGF) gene
transfer is a potential treatment for coronary heart disease. However, only limited data are …

… Markku Laakso … (Reprint requests to Dr Markku Laakso at this address) This work was
supported by a grant from the Academy of Finland. … 960 Laakso …

Background The worldwide increase in type 2 diabetes mellitus is becoming a major health
concern. We aimed to assess the effect of acarbose in preventing or delaying conversion of …

Background Type 2 (non-insulin-dependent) diabetes is associated with a marked increase
in the risk of coronary heart disease. It has been debated whether patients with diabetes …

Large-scale reference data sets of human genetic variation are critical for the medical and
functional interpretation of DNA sequence changes. Here we describe the aggregation and …

Before this question can be answered, the number of parties must be operationally defined
in a way that takes into account their relativesize. Such a number is also needed if one wants …