This work describes a new diffusion MR framework for imaging and modeling of microstructure
that we call q-space trajectory imaging (QTI). The QTI framework consists of two parts: …

This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

Objective: To compare the diagnostic accuracy of CSF biomarkers and amyloid PET for
diagnosing early-stage Alzheimer disease (AD). Methods: From the prospective, longitudinal …

The anisotropy of water diffusion in brain tissue is affected by both disease and development.
This change can be detected using diffusion MRI and is often quantified by the fractional …

Diffusion tensor imaging (DTI) is the method of choice for non-invasive investigations of the
structure of human brain white matter (WM). The results are conventionally reported as maps …

Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion
NMR and MRI the mainstay of most studies seeking to resolve microstructural information in …

In diffusion MRI (dMRI), microscopic diffusion anisotropy can be obscured by orientation
dispersion. Separation of these properties is of high importance, since it could allow dMRI to non…

The structural heterogeneity of tumor tissue can be probed by diffusion MRI (dMRI) in terms
of the variance of apparent diffusivities within a voxel. However, the link between the …

We present the first in vivo application of the filter‐exchange imaging protocol for diffusion
MRI. The protocol allows noninvasive mapping of the rate of water exchange between …

Diffusion MRI is a useful probe of tissue microstructure. The conventional diffusion encoding
sequence, the single pulsed field gradient, has recently been challenged as more general …