In recent years, a new class of designer drugs has appeared on the drugs of abuse market in
many countries, namely, the so-called beta-keto (bk) designer drugs such as mephedrone (…

Since the late 1990s, many derivatives of the α‐pyrrolidinophenone (PPP) drug class
appeared on the drugs of abuse market. The latest compound was described in 2009 to be a …

The information obtained from the chemical analysis of specific human excretion products (biomarkers)
in urban wastewater can be used to estimate the exposure or consumption of the …

In multi‐analyte procedures, sufficient separation is important to avoid interferences, particularly
when using liquid chromatography/mass spectrometry (LC/MS) because of possible ion …

Today, immunoassays and several chromatographic methods are in use for drug screening
in clinical and forensic toxicology and in doping control. For further proof of the authors’ new …

Background: The challenge in systematic toxicological analysis using gas chromatography
and/or liquid chromatography coupled to mass spectrometry is to identify compounds of …

LC–high resolution (HR)-MS well established in proteomics has become more and more
important in bioanalysis of small molecules over the last few years. Its high selectivity and …

Pharmacologic and toxic effects of xenobiotics, such as drugs of abuse, depend on the
genotype and phenotype of an individual, and conversely on the isoenzymes involved in their …

In contrast to GC-MS libraries, currently available LC-MS libraries for toxicological detection
contain besides parent drugs only some main metabolites limiting their applicability for urine …

This paper reviews the metabolism of new designer drugs of abuse that have emerged on
the black market during the last years and is an update of a review published in 2005. The …