Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study

…, SJ Brooks, OG O'Daly, MS Almen… - The Journal of …, 2012 - academic.oup.com
Context: There is growing recognition that a large number of individuals living in Western
society are chronically sleep deprived. Sleep deprivation is associated with an increase in food …

[HTML][HTML] Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents

S Voisin, MS Almén, G Moschonis… - European Journal of …, 2015 - nature.com
The type and the amount of dietary fat have a significant influence on the metabolic
pathways involved in the development of obesity, metabolic syndrome, diabetes type 2 and …

What model organisms and interactomics can reveal about the genetics of human obesity

MJ Williams, MS Almén, R Fredriksson… - Cellular and Molecular …, 2012 - Springer
Genome-wide association studies have identified a number of genes associated with human
body weight. While some of these genes are large fields within obesity research, such as …

The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum …

S Sreedharan, MS Almen, VP Carlini… - The FEBS …, 2011 - Wiley Online Library
The Rhodopsin family of G protein coupled receptors (GPCRs) includes the phylogenetic α‐group
consisting of about 100 human members. The α‐group is the only group of GPCRs …

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

…, D Fridmanis, K Geldnere, JA Jacobsson, MS Almen… - Gene, 2013 - Elsevier
Variations in the FTO gene and near the TMEM18 gene are risk factors for common form of
obesity, but have also been linked with type 2 diabetes (T2D). Our aim was to investigate the …

[PDF][PDF] GWAS identifies a single selective sweep for age of maturation in wild and cultivated Atlantic salmon males

…, G Dahle, GL Wargelius, KA Glover, MS Almén… - bioRxiv, 2015 - biorxiv.org
Background Sea age at sexual maturation displays large plasticity for wild Atlantic salmon
males and varies between 1-5 years. This flexibility can also be observed in domesticated …

[CITATION][C] Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study.

C Benedict, SJ Brooks, OG O'Daly, MS Almèn, A Morell… - academic.oup.com
Objectives, Participants, and Measures: We tested whether the expression of members of
the mitogenic ErbB family was reduced in adipose tissue of insulin-resistant individuals and …

[HTML][HTML] Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

MS Almén, KJV Nordström, R Fredriksson, HB Schiöth - BMC biology, 2009 - Springer
Background Membrane proteins form key nodes in mediating the cell's interaction with the
surroundings, which is one of the main reasons why the majority of drug targets are …

Trends in the exploitation of novel drug targets

M Rask-Andersen, MS Almén, HB Schiöth - Nature reviews Drug …, 2011 - nature.com
The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical
industry and academic biomedical research. To provide an insight into trends in the …

Evolution of Darwin's finches and their beaks revealed by genome sequencing

S Lamichhaney, J Berglund, MS Almén, K Maqbool… - Nature, 2015 - nature.com
Darwin’s finches, inhabiting the Galápagos archipelago and Cocos Island, constitute an iconic
model for studies of speciation and adaptive evolution. Here we report the results of whole…