Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study
Context: There is growing recognition that a large number of individuals living in Western
society are chronically sleep deprived. Sleep deprivation is associated with an increase in food …
society are chronically sleep deprived. Sleep deprivation is associated with an increase in food …
[HTML][HTML] Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents
S Voisin, MS Almén, G Moschonis… - European Journal of …, 2015 - nature.com
The type and the amount of dietary fat have a significant influence on the metabolic
pathways involved in the development of obesity, metabolic syndrome, diabetes type 2 and …
pathways involved in the development of obesity, metabolic syndrome, diabetes type 2 and …
What model organisms and interactomics can reveal about the genetics of human obesity
MJ Williams, MS Almén, R Fredriksson… - Cellular and Molecular …, 2012 - Springer
Genome-wide association studies have identified a number of genes associated with human
body weight. While some of these genes are large fields within obesity research, such as …
body weight. While some of these genes are large fields within obesity research, such as …
The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum …
S Sreedharan, MS Almen, VP Carlini… - The FEBS …, 2011 - Wiley Online Library
The Rhodopsin family of G protein coupled receptors (GPCRs) includes the phylogenetic α‐group
consisting of about 100 human members. The α‐group is the only group of GPCRs …
consisting of about 100 human members. The α‐group is the only group of GPCRs …
Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes
…, D Fridmanis, K Geldnere, JA Jacobsson, MS Almen… - Gene, 2013 - Elsevier
Variations in the FTO gene and near the TMEM18 gene are risk factors for common form of
obesity, but have also been linked with type 2 diabetes (T2D). Our aim was to investigate the …
obesity, but have also been linked with type 2 diabetes (T2D). Our aim was to investigate the …
[PDF][PDF] GWAS identifies a single selective sweep for age of maturation in wild and cultivated Atlantic salmon males
…, G Dahle, GL Wargelius, KA Glover, MS Almén… - bioRxiv, 2015 - biorxiv.org
Background Sea age at sexual maturation displays large plasticity for wild Atlantic salmon
males and varies between 1-5 years. This flexibility can also be observed in domesticated …
males and varies between 1-5 years. This flexibility can also be observed in domesticated …
[CITATION][C] Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study.
Objectives, Participants, and Measures: We tested whether the expression of members of
the mitogenic ErbB family was reduced in adipose tissue of insulin-resistant individuals and …
the mitogenic ErbB family was reduced in adipose tissue of insulin-resistant individuals and …
[HTML][HTML] Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
Background Membrane proteins form key nodes in mediating the cell's interaction with the
surroundings, which is one of the main reasons why the majority of drug targets are …
surroundings, which is one of the main reasons why the majority of drug targets are …
Trends in the exploitation of novel drug targets
M Rask-Andersen, MS Almén, HB Schiöth - Nature reviews Drug …, 2011 - nature.com
The discovery and exploitation of new drug targets is a key focus for both the pharmaceutical
industry and academic biomedical research. To provide an insight into trends in the …
industry and academic biomedical research. To provide an insight into trends in the …
Evolution of Darwin's finches and their beaks revealed by genome sequencing
S Lamichhaney, J Berglund, MS Almén, K Maqbool… - Nature, 2015 - nature.com
Darwin’s finches, inhabiting the Galápagos archipelago and Cocos Island, constitute an iconic
model for studies of speciation and adaptive evolution. Here we report the results of whole…
model for studies of speciation and adaptive evolution. Here we report the results of whole…