The enteric nervous system (ENS) is a network of neurons and glia within the wall of the
gastrointestinal tract that is able to control many aspects of digestive function independently …

• Neuronal diversity in the adult enteric nervous system (ENS) • Developmental appearance
and birthdating of enteric neuron subtypes and glial cells ‐ Developmental appearance of …

Hirschsprung disease (HSCR), which is also called congenital megacolon or intestinal
aganglionosis, is characterized by an absence of enteric (intrinsic) neurons from variable lengths …

10.7554/eLife.42914.001 The enteric nervous system controls a variety of gastrointestinal
functions including intestinal motility. The minimal neuronal circuit necessary to direct …

Coordination of gastrointestinal function relies on joint efforts of enteric neurons and glia,
whose crosstalk is vital for the integration of their activity. To investigate the signaling …

Secretory pathways within dendrites of neurons have been proposed for local transport of
newly synthesized proteins. However, little is known about the dynamics of the local secretory …

Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the “support”
cells of the enteric nervous system, studies over the past 20 years have unveiled a vast …

Background Directed cell migration is essential for normal development. In most of the
migratory cell populations that have been analyzed in detail to date, all of the cells migrate as a …

Background & Aims Cell therapy offers the potential to treat gastrointestinal motility disorders
caused by diseased or absent enteric neurons. We examined whether neurons generated …

Optogenetics and chemogenetics comprise a wide variety of applications in which genetically
encoded actuators and indicators are used to modulate and monitor activity with high …