[HTML][HTML] Diversity in clinical and biomedical research: a promise yet to be fulfilled

…, N Thakur, M Pino-Yanes, NE Barcelo, MJ White… - PLoS …, 2015 - journals.plos.org
… The funders had no role in writing the article, decision to publish, or preparation of the
manuscript but did provide feedback on the precision of wording regarding the award rate …

Diagnostic tools for hypertension and salt sensitivity testing

RA Felder, MJ White, SM Williams… - Current opinion in …, 2013 - journals.lww.com
Accurate testing of salt sensitivity is not only laborious but also expensive, and with low
patient compliance. Patients who have normal blood pressure but are salt-sensitive cannot be …

Whole-genome sequencing of pharmacogenetic drug response in racially diverse children with asthma

ACY Mak, MJ White, WL Eckalbar… - American journal of …, 2018 - atsjournals.org
Rationale: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide.
There are significant racial/ethnic differences in albuterol drug response. Objectives: To …

[PDF][PDF] Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

…, JG Taylor, MJ Telen, HK Tiwari, RP Tracy, MJ White… - Cell Genomics, 2022 - cell.com
Genetic studies on telomere length are important for understanding age-related diseases.
Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here, we …

Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study

MJ White, O Risse-Adams, P Goddard, MG Contreras… - Immunogenetics, 2016 - Springer
Asthma, an inflammatory disorder of the airways, is the most common chronic disease of
children worldwide. There are significant racial/ethnic disparities in asthma prevalence, …

Air pollution and lung function in minority youth with asthma in the GALA II (Genes–Environments and Admixture in Latino Americans) and SAGE II (Study of African …

AM Neophytou, MJ White, SS Oh, N Thakur… - American journal of …, 2016 - atsjournals.org
Rationale: Adverse effects of exposures to ambient air pollution on lung function are well
documented, but evidence in racial/ethnic minority children is lacking. Objectives: To assess …

A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma

…, MJ White, ME McGarry, N Thakur, J Galanter… - The …, 2019 - nature.com
Short-acting β 2 -adrenergic receptor agonists (SABAs) are the most commonly prescribed
asthma medications worldwide. Response to SABAs is measured as bronchodilator drug …

[HTML][HTML] On the cross-population generalizability of gene expression prediction models

…, MJ White, WL Eckalbar, AW Dahl, J Mefford… - PLoS …, 2020 - journals.plos.org
The genetic control of gene expression is a core component of human physiology. For the
past several years, transcriptome-wide association studies have leveraged large datasets of …

Sequencing and imputation in GWAS: Cost‐effective strategies to increase power and genomic coverage across diverse populations

…, ST Weiss, EG Burchard, MJ White… - Genetic …, 2020 - Wiley Online Library
A key aim for current genome‐wide association studies (GWAS) is to interrogate the full
spectrum of genetic variation underlying human traits, including rare variants, across populations…

[PDF][PDF] Ancestry-dependent enrichment of deleterious homozygotes in runs of homozygosity

ZA Szpiech, ACY Mak, MJ White, D Hu, C Eng… - The American Journal of …, 2019 - cell.com
Runs of homozygosity (ROH) are important genomic features that manifest when an
individual inherits two haplotypes that are identical by descent. Their length distributions are …