Hansen’s disease (HD), or leprosy, continues to be endemic in many parts of the world.
Although multidrug therapy (MDT) is successful in curing a large number of patients, some of …

Mycobacterium abscessus (Mab) has emerged as a challenging threat to individuals with
cystic fibrosis. Infections caused by this pathogen are often impossible to treat due to the …

Computational Saturation Mutagenesis is an in-silico approach that employs systematic
mutagenesis of each amino acid residue in the protein to all other amino acid types and predicts …

Focal Adhesion Kinase signaling pathway and its functions have been involved in the
development and aggressiveness of tumor malignancy, it then presents a promising cancer …

Pseudomonas aeruginosa is of major concern for cystic fibrosis patients where this infection
can be fatal. With the emergence of drug-resistant strains, there is an urgent need to …

Trehalose is an essential disaccharide for mycobacteria and a key constituent of several
cell wall glycolipids with fundamental roles in pathogenesis. Mycobacteria possess two …

Leprosy, caused by Mycobacterium leprae (M. leprae), is treated with a multidrug regimen
comprising Dapsone, Rifampicin, and Clofazimine. These drugs exhibit bacteriostatic, …

Tanto la señalización como otras funciones mediadas por la quinasa de adhesión focal (FAK)
están intrínsecamente involucradas en el desarrollo de la malignidad tumoral, lo que …

El cáncer de colon presenta una distribución geográfica inusual lo que sugiere que haya
una nueva causa ambiental, como una infección viral. En este Trabajo Fin de Máster se …

Pseudomonas aeruginosa is an opportunistic pathogen and is of major concern for cystic
fibrosis patients where this infection can be fatal. With the emergence of drug-resistant strains …