Blood-based biomarkers for Alzheimer's disease: towards clinical implementation

…, WM van der Flier, MM Mielke, M Del Campo - The Lancet …, 2022 - thelancet.com
For many years, blood-based biomarkers for Alzheimer's disease seemed unattainable, but
recent results have shown that they could become a reality. Convincing data generated with …

Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update

M Del Campo, B Mollenhauer, A Bertolotto… - Biomarkers in …, 2012 - Future Medicine
Early diagnosis of neurodegenerative disorders such as Alzheimer’s (AD) or Parkinson’s
disease (PD) is needed to slow down or halt the disease at the earliest stage. Cerebrospinal …

New developments of biofluid‐based biomarkers for routine diagnosis and disease trajectories in frontotemporal dementia

M Del Campo, H Zetterberg, S Gandy… - Alzheimer's & …, 2022 - Wiley Online Library
Frontotemporal dementia (FTD) covers a spectrum of neurodegenerative disorders with
different phenotypes, genetic backgrounds, and pathological states. Its clinicopathological …

Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum

LHH Meeter, EG Vijverberg, M Del Campo… - Neurology, 2018 - AAN Enterprises
Objective To examine the clinical value of neurofilament light chain (NfL) and the phospho-tau/total
tau ratio (p/t-tau) across the entire frontotemporal dementia (FTD) spectrum in a large…

CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels

M Del Campo, CFW Peeters, ECB Johnson, L Vermunt… - Nature aging, 2022 - nature.com
Abstract Development of disease-modifying therapies against Alzheimer’s disease (AD)
requires biomarkers reflecting the diverse pathological pathways specific for AD. We measured …

Host recognition by the tobacco hornworm is mediated by a host plant compound

ML del Campo, CI Miles, FC Schroeder, C Mueller… - Nature, 2001 - nature.com
It is generally believed that animals make decisions about the selection of mates, kin or food
on the basis of pre-constructed recognition templates. These templates can be innate or …

[HTML][HTML] CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer s disease

M Del Campo, L Vermunt, CFW Peeters… - Nature …, 2023 - nature.com
Diagnosis of dementia with Lewy bodies (DLB) is challenging and specific biofluid biomarkers
are highly needed. We employed proximity extension-based assays to measure 665 …

Pinoresinol: A lignol of plant origin serving for defense in a caterpillar

FC Schroeder, ML Del Campo… - Proceedings of the …, 2006 - National Acad Sciences
Pinoresinol, a lignan of wide distribution in plants, is found to occur as a minor component in
the defensive secretion produced by glandular hairs of caterpillars of the cabbage butterfly, …

Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers

…, B Borroni, R Laforce Jr, M Del Campo… - Annals of clinical …, 2018 - Wiley Online Library
Objective To evaluate poly( GP ), a dipeptide repeat protein, and neurofilament light chain (NfL)
as biomarkers in presymptomatic C9orf72 repeat expansion carriers and patients with …

CSF proteomics in autosomal dominant Alzheimer's disease highlights parallels with sporadic disease

…, YAL Pijnenburg, WM Van Der Flier, M Del Campo… - Brain, 2023 - academic.oup.com
Autosomal dominant Alzheimer’s disease (ADAD) offers a unique opportunity to study
pathophysiological changes in a relatively young population with few comorbidities. A …