After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both : Kraepelin, E., 1919/1971. Dementia praecox. …

In animals, exposure to severe stress can damage the hippocampus. Recent human studies
show smaller hippocampal volume in individuals with the stress-related psychiatric …

We examined the status of the neural network mediating the default mode of brain function,
which typically exhibits greater activation during rest than during task, in patients in the early …

Background. Data from postmortem, CT, and magnetic resonance imaging (MRI) studies
indicate that patients with schizophrenia may have anatomical abnormalities of the left temporal …

This study used quantitative volumetric magnetic resonance imaging techniques to explore
the neuroanatomic correlates of chronic, combat-related posttraumatic stress disorder (PTSD…

Both post-mortem and neuroimaging studies have contributed significantly to what we know
about the brain and schizophrenia. MRI studies of volumetric reduction in several brain …

Structural magnetic resonance imaging (MRI) data have provided much evidence in support
of our current view that schizophrenia is a brain disorder with altered brain structure, and …

Schizophrenia has been conceptualized as a failure of cognitive integration, and abnormalities
in neural circuitry (particularly inhibitory interneurons) have been proposed as a basis for …

Background Basic science studies at the neuronal systems level have indicated that gamma-range
(30-50 Hz) neural synchronization may be a key mechanism of information …

Current views of schizophrenia suggest that it results from abnormalities in neural circuitry,
but empirical evidence in the millisecond range of neural activity has been difficult to obtain. …