Significance testing of synergistic/antagonistic, dose level‐dependent, or dose ratio‐dependent effects in mixture dose‐response analysis
MJ Jonker, C Svendsen, JJM Bedaux… - … and Chemistry: An …, 2005 - Wiley Online Library
In ecotoxicology, the state of the art for effect assessment of chemical mixtures is through
multiple dose—response analysis of single compounds and their combinations. Investigating …
multiple dose—response analysis of single compounds and their combinations. Investigating …
[HTML][HTML] Extreme slow growth as alternative strategy to survive deep starvation in bacteria
Bacteria can become dormant or form spores when they are starved for nutrients. Here, we
find that non-sporulating Bacillus subtilis cells can survive deep starvation conditions for …
find that non-sporulating Bacillus subtilis cells can survive deep starvation conditions for …
Expression of distinct maternal and somatic 5.8 S, 18S, and 28S rRNA types during zebrafish development
…, U Nehrdich, HP Spaink, H Rauwerda, MJ Jonker… - Rna, 2017 - rnajournal.cshlp.org
There is mounting evidence that the ribosome is not a static translation machinery, but a cell-specific,
adaptive system. Ribosomal variations have mostly been studied at the protein …
adaptive system. Ribosomal variations have mostly been studied at the protein …
Differences in gene expression profiles between human preimplantation embryos cultured in two different IVF culture media
…, JG Derhaag, E Mantikou, MJ Jonker… - Human …, 2015 - academic.oup.com
STUDY QUESTION Is gene expression in human preimplantation embryos affected by the
medium used for embryo culture in vitro during an IVF treatment? SUMMARY ANSWER Six …
medium used for embryo culture in vitro during an IVF treatment? SUMMARY ANSWER Six …
Dynamics of mutations during development of resistance by Pseudomonas aeruginosa against five antibiotics
Pseudomonas aeruginosa is an opportunistic pathogen that causes considerable morbidity
and mortality, specifically during intensive care. Antibiotic-resistant variants of this organism …
and mortality, specifically during intensive care. Antibiotic-resistant variants of this organism …
[HTML][HTML] Transcriptome profiling of developmental and xenobiotic responses in a keystone soil animal, the oligochaete annelid Lumbricus rubellus
J Owen, BA Hedley, C Svendsen, J Wren, MJ Jonker… - Bmc Genomics, 2008 - Springer
Background Natural contamination and anthropogenic pollution of soils are likely to be major
determinants of functioning and survival of keystone invertebrate taxa. Soil animals will …
determinants of functioning and survival of keystone invertebrate taxa. Soil animals will …
[HTML][HTML] Single cell transcriptomics of neighboring hyphae of Aspergillus niger
C de Bekker, O Bruning, MJ Jonker, TM Breit… - Genome biology, 2011 - Springer
Single cell profiling was performed to assess differences in RNA accumulation in neighboring
hyphae of the fungus Aspergillus niger. A protocol was developed to isolate and amplify …
hyphae of the fungus Aspergillus niger. A protocol was developed to isolate and amplify …
[HTML][HTML] The Arabidopsis SUMO E3 ligase SIZ1 mediates the temperature dependent trade-off between plant immunity and growth
…, M Arroyo-Mateos, PFK Wackers, MJ Jonker… - PLoS …, 2018 - journals.plos.org
Increased ambient temperature is inhibitory to plant immunity including auto-immunity.
SNC1-dependent auto-immunity is, for example, fully suppressed at 28C. We found that the …
SNC1-dependent auto-immunity is, for example, fully suppressed at 28C. We found that the …
Toxicity of binary mixtures of cadmium‐copper and carbendazim‐copper to the nematode Caenorhabditis elegans
MJ Jonker, AM Piskiewicz, NII Castellà… - … and Chemistry: An …, 2004 - Wiley Online Library
For ecological risk assessment, the additive model may be used to empirically predict toxic
mixture effects. Detailed toxicity tests were performed to determine whether effects of mixtures …
mixture effects. Detailed toxicity tests were performed to determine whether effects of mixtures …
Life spanning murine gene expression profiles in relation to chronological and pathological aging in multiple organs
MJ Jonker, JPM Melis, RV Kuiper… - Aging cell, 2013 - Wiley Online Library
Aging and age‐related pathology is a result of a still incompletely understood intricate web
of molecular and cellular processes. We present a C 57 BL /6 J female mice in vivo aging …
of molecular and cellular processes. We present a C 57 BL /6 J female mice in vivo aging …