User profiles for Martin Frejno

Martin Frejno

Technical University of Munich
Verified email at tum.de
Cited by 2091

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

…, J Zecha, A Asplund, L Li, C Meng, M Frejno… - Molecular systems …, 2019 - embopress.org
Genome‐, transcriptome‐ and proteome‐wide measurements provide insights into how
biological systems are regulated. However, fundamental aspects relating to which human …

Mass-spectrometry-based draft of the Arabidopsis proteome

J Mergner, M Frejno, M List, M Papacek, X Chen… - Nature, 2020 - nature.com
Plants are essential for life and are extremely diverse organisms with unique molecular
capabilities 1 . Here we present a quantitative atlas of the transcriptomes, proteomes and …

ProteomicsDB

T Schmidt, P Samaras, M Frejno… - Nucleic acids …, 2018 - academic.oup.com
ProteomicsDB ( https://www.ProteomicsDB.org ) is a protein-centric in-memory database for
the exploration of large collections of quantitative mass spectrometry-based proteomics data…

ProteomicsDB: a multi-omics and multi-organism resource for life science research

P Samaras, T Schmidt, M Frejno… - Nucleic acids …, 2020 - academic.oup.com
ProteomicsDB ( https://www.ProteomicsDB.org ) started as a protein-centric in-memory
database for the exploration of large collections of quantitative mass spectrometry-based …

Mass spectrometry-based draft of the mouse proteome

…, P Samaras, Y Bian, C Meng, A Coluccio, M Frejno… - Nature …, 2022 - nature.com
The laboratory mouse ranks among the most important experimental systems for biomedical
research and molecular reference maps of such models are essential informational tools. …

[HTML][HTML] Ceramide synthase 5 is essential to maintain C16: 0-ceramide pools and contributes to the development of diet-induced obesity

D Gosejacob, PS Jäger, K Vom Dorp, M Frejno… - Journal of Biological …, 2016 - ASBMB
Ceramides are bioactive sphingolipids, which are composed of sphingoid bases carrying
acyl chains of various lengths. Ceramides are synthesized by a family of six ceramide …

moCluster: identifying joint patterns across multiple omics data sets

C Meng, D Helm, M Frejno, B Kuster - Journal of proteome …, 2016 - ACS Publications
Increasingly, multiple omics approaches are being applied to understand the complexity of
biological systems. Yet, computational approaches that enable the efficient integration of …

[HTML][HTML] Proteome activity landscapes of tumor cell lines determine drug responses

M Frejno, C Meng, B Ruprecht, T Oellerich… - Nature …, 2020 - nature.com
Integrated analysis of genomes, transcriptomes, proteomes and drug responses of cancer
cell lines (CCLs) is an emerging approach to uncover molecular mechanisms of drug action. …

[PDF][PDF] THADA regulates the organismal balance between energy storage and heat production

…, M Males, S Mueller, M Jabs, M Muelleder, M Frejno… - Developmental Cell, 2017 - cell.com
Human susceptibility to obesity is mainly genetic, yet the underlying evolutionary drivers
causing variation from person to person are not clear. One theory rationalizes that populations …

INFERYS rescoring: Boosting peptide identifications and scoring confidence of database search results

…, A Huhmer, B Delanghe, M Frejno - Rapid …, 2021 - Wiley Online Library
Database search engines for bottom‐up proteomics largely ignore peptide fragment ion
intensities during the automated scoring of tandem mass spectra against protein databases. …