User profiles for Martin Garrido-Rodriguez
Martin Garrido-RodriguezEMBL Verified email at embl.de Cited by 734 |
[HTML][HTML] Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data
The growing availability of single-cell data, especially transcriptomics, has sparked an
increased interest in the inference of cell-cell communication. Many computational tools were …
increased interest in the inference of cell-cell communication. Many computational tools were …
[HTML][HTML] Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1
L Casares, V García, M Garrido-Rodríguez, E Millán… - Redox Biology, 2020 - Elsevier
Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great
attention for its therapeutic potential against different pathologies including skin diseases. …
attention for its therapeutic potential against different pathologies including skin diseases. …
Integrating knowledge and omics to decipher mechanisms via large‐scale models of signaling networks
Signal transduction governs cellular behavior, and its dysregulation often leads to human
disease. To understand this process, we can use network models based on prior knowledge, …
disease. To understand this process, we can use network models based on prior knowledge, …
[HTML][HTML] FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
…, A Correa-Sáez, M Garrido-Rodríguez… - Cell Death & …, 2023 - nature.com
FBXW7 is a member of the F-box protein family, which functions as the substrate recognition
component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its …
component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its …
[HTML][HTML] A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival
…, R Jiménez-Izquierdo, M Garrido-Rodríguez… - Cell Death & …, 2022 - nature.com
The cell division cycle 25A (CDC25A) phosphatase is a key regulator of cell cycle progression
that acts on the phosphorylation status of Cyclin–Cyclin-dependent kinase complexes, …
that acts on the phosphorylation status of Cyclin–Cyclin-dependent kinase complexes, …
[HTML][HTML] Updating dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2): molecular basis, functions and role in diseases
…, R Jiménez-Izquierdo, M Garrido-Rodríguez… - Cellular and Molecular …, 2020 - Springer
Members of the dual-specificity tyrosine-regulated kinase (DYRKs) subfamily possess a
distinctive capacity to phosphorylate tyrosine, serine, and threonine residues. Among the DYRK …
distinctive capacity to phosphorylate tyrosine, serine, and threonine residues. Among the DYRK …
Metabolomic profiling of human lung tumor tissues–nucleotide metabolism as a candidate for therapeutic interventions and biomarkers
…, C Jiménez‐Jiménez, M Garrido‐Rodríguez… - Molecular …, 2018 - Wiley Online Library
Although metabolomics has attracted considerable attention in the field of lung cancer (LC)
detection and management, only a very limited number of works have applied it to tissues. As …
detection and management, only a very limited number of works have applied it to tissues. As …
Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis
A García-Martín, M Garrido-Rodríguez… - Biochemical …, 2019 - Elsevier
The endocannabinoid system (ECS) may play a role in the pathophysiology of systemic
sclerosis (SSc). Cannabinoids acting as dual PPARγ/CB 2 agonists, such as VCE-004.8 and …
sclerosis (SSc). Cannabinoids acting as dual PPARγ/CB 2 agonists, such as VCE-004.8 and …
Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity
B Palomares, F Ruiz-Pino, M Garrido-Rodriguez… - Biochemical …, 2020 - Elsevier
Medicinal cannabis has remarkable therapeutic potential, but its clinical use is limited by the
psychotropic activity of Δ9-tetrahydrocannabinol (Δ9-THC). However, the biological profile …
psychotropic activity of Δ9-tetrahydrocannabinol (Δ9-THC). However, the biological profile …
[HTML][HTML] Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis
…, A García-Martin, M Garrido-Rodríguez… - Neurobiology of …, 2020 - Elsevier
Multiple Sclerosis (MS) is characterized by a combination of inflammatory and neurodegenerative
processes in the spinal cord and the brain. Natural and synthetic cannabinoids such …
processes in the spinal cord and the brain. Natural and synthetic cannabinoids such …