Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors
The basis for differences in activity-dependent trafficking of AMPA receptors (AMPARs) and
NMDA receptors (NMDARs) remains unclear. Using single-molecule tracking, we found …
NMDA receptors (NMDARs) remains unclear. Using single-molecule tracking, we found …
Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity
Many synapses in the mature CNS are wrapped by a dense extracellular matrix (ECM). Using
single-particle tracking and fluorescence recovery after photobleaching, we found that this …
single-particle tracking and fluorescence recovery after photobleaching, we found that this …
Surface mobility of postsynaptic AMPARs tunes synaptic transmission
AMPA glutamate receptors (AMPARs) mediate fast excitatory synaptic transmission. Upon
fast consecutive synaptic stimulation, transmission can be depressed. Recuperation from fast …
fast consecutive synaptic stimulation, transmission can be depressed. Recuperation from fast …
[PDF][PDF] Bassoon specifically controls presynaptic P/Q-type Ca2+ channels via RIM-binding protein
…, S Romorini, C Montenegro-Venegas, M Heine… - Neuron, 2014 - cell.com
Voltage-dependent Ca 2+ channels (Ca V s) represent the principal source of Ca 2+ ions
that trigger evoked neurotransmitter release from presynaptic boutons. Ca 2+ influx is …
that trigger evoked neurotransmitter release from presynaptic boutons. Ca 2+ influx is …
Unified quantitative model of AMPA receptor trafficking at synapses
…, M Mondin, M Garcia, M Heine… - Proceedings of the …, 2012 - National Acad Sciences
Trafficking of AMPA receptors (AMPARs) plays a key role in synaptic transmission. However,
a general framework integrating the two major mechanisms regulating AMPAR delivery at …
a general framework integrating the two major mechanisms regulating AMPAR delivery at …
NMDA receptor surface mobility depends on NR2A-2B subunits
The NR2 subunit composition of NMDA receptors (NMDARs) varies during development,
and this change is important in NMDAR-dependent signaling. In particular, synaptic NMDAR …
and this change is important in NMDAR-dependent signaling. In particular, synaptic NMDAR …
Exercise therapy for fatigue in multiple sclerosis
M Heine, I van de Port, MB Rietberg… - Cochrane database …, 2015 - cochranelibrary.com
Background Multiple sclerosis (MS) is an immune‐mediated disease of the central nervous
system affecting an estimated 1.3 million people worldwide. It is characterised by a variety of …
system affecting an estimated 1.3 million people worldwide. It is characterised by a variety of …
[PDF][PDF] Diffusional trapping of GluR1 AMPA receptors by input-specific synaptic activity
Synaptic activity regulates the postsynaptic accumulation of AMPA receptors over timescales
ranging from minutes to days. Indeed, the regulated trafficking and mobility of GluR1 AMPA …
ranging from minutes to days. Indeed, the regulated trafficking and mobility of GluR1 AMPA …
[PDF][PDF] Single nanoparticle photothermal tracking (SNaPT) of 5-nm gold beads in live cells
Tracking individual nano-objects in live cells during arbitrary long times is a ubiquitous
need in modern biology. We present here a method for tracking individual 5-nm gold …
need in modern biology. We present here a method for tracking individual 5-nm gold …
Unravelling 'low-resource settings': a systematic scoping review with qualitative content analysis
Introduction The effects of healthcare-related inequalities are most evident in low-resource
settings. Such settings are often not explicitly defined, and umbrella terms which are easier to …
settings. Such settings are often not explicitly defined, and umbrella terms which are easier to …