User profiles for Martin J. Lercher

Martin J. Lercher

Professor of Computational Cell Biology, Heinrich Heine University Düsseldorf
Verified email at hhu.de
Cited by 13645

PopGenome: an efficient Swiss army knife for population genomic analyses in R

…, SE Ramos-Onsins, MJ Lercher - Molecular biology …, 2014 - academic.oup.com
Although many computer programs can perform population genetics calculations, they are
typically limited in the analyses and data input formats they offer; few applications can …

The evolutionary dynamics of eukaryotic gene order

LD Hurst, C Pál, MJ Lercher - Nature Reviews Genetics, 2004 - nature.com
In eukaryotes, unlike in bacteria, gene order has typically been assumed to be random.
However, the first statistically rigorous analyses of complete genomes, together with the …

An integrated view of protein evolution

C Pál, B Papp, MJ Lercher - Nature reviews genetics, 2006 - nature.com
Why do proteins evolve at different rates? Advances in systems biology and genomics have
facilitated a move from studying individual proteins to characterizing global cellular factors. …

Clustering of housekeeping genes provides a unified model of gene order in the human genome

MJ Lercher, AO Urrutia, LD Hurst - Nature genetics, 2002 - nature.com
It is often supposed that, except for tandem duplicates, genes are randomly distributed
throughout the human genome. However, recent analyses suggest that when all the genes …

Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees

B Subramanian, S Gao, MJ Lercher, S Hu… - Nucleic acids …, 2019 - academic.oup.com
Evolview is an interactive tree visualization tool designed to help researchers in visualizing
phylogenetic trees and in annotating these with additional information. It offers the user with …

Adaptive evolution of bacterial metabolic networks by horizontal gene transfer

C Pál, B Papp, MJ Lercher - Nature genetics, 2005 - nature.com
Numerous studies have considered the emergence of metabolic pathways 1 , but the
modes of recent evolution of metabolic networks are poorly understood. Here, we integrate …

Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees

Z He, H Zhang, S Gao, MJ Lercher… - Nucleic acids …, 2016 - academic.oup.com
Evolview is an online visualization and management tool for customized and annotated
phylogenetic trees. It allows users to visualize phylogenetic trees in various formats, customize …

Gene transfer from bacteria and archaea facilitated evolution of an extremophilic eukaryote

…, D Gagneul, NE Dickenson, C Oesterhelt, MJ Lercher… - Science, 2013 - science.org
Some microbial eukaryotes, such as the extremophilic red alga Galdieria sulphuraria, live in
hot, toxic metal-rich, acidic environments. To elucidate the underlying molecular …

EvolView, an online tool for visualizing, annotating and managing phylogenetic trees

H Zhang, S Gao, MJ Lercher, S Hu… - Nucleic acids …, 2012 - academic.oup.com
EvolView is a web application for visualizing, annotating and managing phylogenetic trees.
First, EvolView is a phylogenetic tree viewer and customization tool; it visualizes trees in …

Human SNP variability and mutation rate are higher in regions of high recombination

MJ Lercher, LD Hurst - Trends in genetics, 2002 - cell.com
Understanding the co-variation of nucleotide diversity and local recombination rates is
important both for the mapping of disease-associated loci and in understanding the causes of …