User profiles for Martin Piskacek

Martin Piskacek

Department of Pathological Physiology, Faculty of Medicine, Masaryk University
Verified email at med.muni.cz
Cited by 678

[HTML][HTML] Nine-amino-acid transactivation domain: establishment and prediction utilities

S Piskacek, M Gregor, M Nemethova, M Grabner… - Genomics, 2007 - Elsevier
Here we describe the establishment and prediction utilities for a novel nine-amino-acid
transactivation domain, 9aa TAD, that is common to the transactivation domains of a large …

Conditional knockdown of hMRS2 results in loss of mitochondrial Mg + uptake and cell death

M Piskacek, L Zotova, G Zsurka… - Journal of cellular and …, 2009 - Wiley Online Library
The human gene MRS2L encodes a mitochondrial protein distantly related to CorA Mg 2+
transport proteins. Constitutive shRNA‐mediated knockdown of hMRS2 in human HEK‐293 …

[HTML][HTML] The 9aaTAD transactivation domains: from Gal4 to p53

M Piskacek, M Havelka, M Rezacova, A Knight - PloS one, 2016 - journals.plos.org
The family of the Nine amino acid Transactivation Domain, 9aaTAD family, comprises currently
over 40 members. The 9aaTAD domains are universally recognized by the transcriptional …

[HTML][HTML] Functionally suppressive CD8 T regulatory cells are increased in patients with multiple myeloma: a cause for immune impairment

KR Muthu Raja, L Kubiczkova, L Rihova, M Piskacek… - PloS one, 2012 - journals.plos.org
Background Multiple myeloma (MM) is a plasma cell malignancy frequently associated with
impaired immune cell numbers and functions. In MM, several studies have previously shown …

[HTML][HTML] Functional Analysis of the Zn2Cys6Transcription Factors Oaf1p and Pip2p: DIFFERENT ROLES IN FATTY ACID INDUCTION OF β-OXIDATION …

U Baumgartner, B Hamilton, M Piskacek, H Ruis… - Journal of biological …, 1999 - ASBMB
Fatty acid induction of the peroxisomal β-oxidation machinery in Saccharomyces cerevisiaeinvolves
transcriptional control of genes regulated by the oleate response element (ORE). …

[HTML][HTML] Clozapine reverses dysfunction of glutamatergic neurons derived from clozapine-responsive schizophrenia patients

…, J Horinkova, L Lacinova, M Piskacek… - Frontiers in Cellular …, 2022 - frontiersin.org
The cellular pathology of schizophrenia and the potential of antipsychotics to target underlying
neuronal dysfunctions are still largely unknown. We employed glutamatergic neurons …

A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18

…, M Hoeth, M Piskacek, H Mayer, R de Martin - Biochemical and …, 2007 - Elsevier
Sox transcription factors are members of the Sry-related protein family that play multiple roles
mainly during development. Sox18 has been implicated in the development of hair follicles …

[HTML][HTML] Blocking of EphA2 on endometrial tumor cells reduces susceptibility to Vδ1 gamma-delta T-cell-mediated killing

R Hudecek, B Kohlova, I Siskova, M Piskacek… - Frontiers in …, 2021 - frontiersin.org
Background Endometriosis is a common gynecological disease characterized by the presence
of endometrial tissue outside the uterus causing chronic inflammation, severe pain, and …

[HTML][HTML] Shared structural features of the 9aaTAD family in complex with CBP

M Piskacek, A Vasku, R Hajek, A Knight - Molecular BioSystems, 2015 - pubs.rsc.org
A number of transactivation domains for transcription factors including p53, E2A/HEB, MLL,
cMyb, CREB, FOXO3, Gcn4, Oaf1 and Pdr1 have been reported to interact with the KIX …

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

…, I Gudernova, J Krenova, S Ghosh, M Piskacek… - Science …, 2018 - science.org
Sustained activation of extracellular signal–regulated kinase (ERK) drives pathologies caused
by mutations in fibroblast growth factor receptors (FGFRs). We previously identified the …