User profiles for Martin Witzenrath
 | martin witzenrathCharité - Universitätsmedizin Berlin Verified email at charite.de Cited by 16798 |
[HTML][HTML] SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the rapidly
unfolding coronavirus disease 2019 (COVID-19) pandemic 1, 2. Clinical manifestations of …
unfolding coronavirus disease 2019 (COVID-19) pandemic 1, 2. Clinical manifestations of …
[HTML][HTML] COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
To investigate the immune response and mechanisms associated with severe coronavirus
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …
[PDF][PDF] Severe COVID-19 is marked by a dysregulated myeloid cell compartment
Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract infection, however,
a subset of patients progress to severe disease and respiratory failure. The mechanism …
a subset of patients progress to severe disease and respiratory failure. The mechanism …
Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation
…, S Koidl, G Thurston, NW Gale, M Witzenrath… - Nature medicine, 2006 - nature.com
The angiopoietins Ang-1 and Ang-2 have been identified as ligands of the receptor tyrosine
kinase Tie-2 (refs. 1 , 2 ). Paracrine Ang-1–mediated activation of Tie-2 acts as a regulator of …
kinase Tie-2 (refs. 1 , 2 ). Paracrine Ang-1–mediated activation of Tie-2 acts as a regulator of …
Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021
…, R Van den Berg-Emons, E Wallin, M Witzenrath… - Jama, 2022 - jamanetwork.com
Importance Some individuals experience persistent symptoms after initial symptomatic
SARS-CoV-2 infection (often referred to as Long COVID). Objective To estimate the proportion of …
SARS-CoV-2 infection (often referred to as Long COVID). Objective To estimate the proportion of …
[PDF][PDF] Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection
The COVID-19 pandemic is an unprecedented global challenge, and point-of-care
diagnostic classifiers are urgently required. Here, we present a platform for ultra-high-throughput …
diagnostic classifiers are urgently required. Here, we present a platform for ultra-high-throughput …
[PDF][PDF] A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model
…, K Skriner, AC Hocke, S Hippenstiel, M Witzenrath… - Cell, 2020 - cell.com
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19),
manifesting with respiratory symptoms and multi-organ dysfunction. Detailed …
manifesting with respiratory symptoms and multi-organ dysfunction. Detailed …
[HTML][HTML] Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters
Vaccines play a critical role in combating the COVID-19 pandemic. Future control of the
pandemic requires improved vaccines with high efficacy against newly emerging SARS-CoV-2 …
pandemic requires improved vaccines with high efficacy against newly emerging SARS-CoV-2 …
Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report
…, M Takata, R Tuder, S Uhlig, M Witzenrath… - American journal of …, 2022 - atsjournals.org
Advancements in methods, technology, and our understanding of the pathobiology of lung
injury have created the need to update the definition of experimental acute lung injury (ALI). …
injury have created the need to update the definition of experimental acute lung injury (ALI). …
[PDF][PDF] A time-resolved proteomic and prognostic map of COVID-19
COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …
to severe organ damage and death. We characterized the time-dependent progression of …