Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF
RN Hvorup, BA Goetz, M Niederer, K Hollenstein… - Science, 2007 - science.org
BtuCD is an adenosine triphosphate–binding cassette (ABC) transporter that translocates
vitamin B 12 from the periplasmic binding protein BtuF into the cytoplasm of Escherichia coli. …
vitamin B 12 from the periplasmic binding protein BtuF into the cytoplasm of Escherichia coli. …
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins
…, J Kowal, EV Filippova, M Niederer… - Proceedings of the …, 2021 - National Acad Sciences
With conformation-specific nanobodies being used for a wide range of structural, biochemical,
and cell biological applications, there is a demand for antigen-binding fragments (Fabs) …
and cell biological applications, there is a demand for antigen-binding fragments (Fabs) …
[HTML][HTML] Copper starvation-inducible protein for cytochrome oxidase biogenesis in Bradyrhizobium japonicum
…, HM Fischer, R Brogioli, M Niederer… - Journal of Biological …, 2012 - ASBMB
Microarray analysis of Bradyrhizobium japonicum grown under copper limitation uncovered
five genes named pcuABCDE, which are co-transcribed and co-regulated as an operon. The …
five genes named pcuABCDE, which are co-transcribed and co-regulated as an operon. The …
Structural and functional investigations of bacterial MFS-and MATE-type multidrug transporters
M Niederer - 2012 - research-collection.ethz.ch
Cells and organelles are surrounded by biological membranes that serve as selective
barriers. Import of nutrients and export of waste products across membranes are mediated by …
barriers. Import of nutrients and export of waste products across membranes are mediated by …
[PDF][PDF] Structural and functional characterization of the multidrug ABC transporter Sav1866 from Staphylococcus aureus
RJP Dawson - 2007 - research-collection.ethz.ch
ATP binding cassette (ABC) transporters are integral membrane proteins that actively transport
chemically diverse substrates across the lipid bilayers of cellular membranes. Clinically …
chemically diverse substrates across the lipid bilayers of cellular membranes. Clinically …
Impact of clinical risk scores and BRAF V600E mutation status on outcome in papillary thyroid cancer
SM Niederer-Wüst, W Jochum, D Förbs, M Brändle… - Surgery, 2015 - Elsevier
Background To evaluate the relationship between the BRAF V600E mutation and clinicopathologic
parameters and to assess the impact of the BRAF V600E mutation and established …
parameters and to assess the impact of the BRAF V600E mutation and established …
Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
…, A De Martin, F Ronchi, K Van Der Borght, R Niederer… - Science, 2019 - science.org
Myocarditis can develop into inflammatory cardiomyopathy through chronic stimulation of
myosin heavy chain 6–specific T helper (T H )1 and T H 17 cells. However, mechanisms …
myosin heavy chain 6–specific T helper (T H )1 and T H 17 cells. However, mechanisms …
[HTML][HTML] Comprehensive Grading System for Experimental Autoimmune Uveitis in Mice
Experimental autoimmune uveitis (EAU) is the most commonly used animal model to study
the progression of chronic uveitis and to test various therapies to treat the disease. However, …
the progression of chronic uveitis and to test various therapies to treat the disease. However, …
Validation of a smartphone-based measurement tool for the quantification of level walking
M Furrer, L Bichsel, M Niederer, H Baur, S Schmid - Gait & posture, 2015 - Elsevier
Introduction It is important to assess and quantify gait in order to determine the severity of
impairments during gait and to evaluate therapeutic interventions. However, laboratory gait …
impairments during gait and to evaluate therapeutic interventions. However, laboratory gait …
Studies of conformational rearrangements during the transport cycle of bacterial ABC transporters
BA Götz - 2009 - research-collection.ethz.ch
… Cross-linking studies were also performed with mutants engineered in the periplasmic
surface of the TMDs (T276S and A281C) (done by Martina Niederer from our laboratory). In the …
surface of the TMDs (T276S and A281C) (done by Martina Niederer from our laboratory). In the …