User profiles for Mary Dasso
 | Mary DassoSenior Investigator, NICHD Verified email at mail.nih.gov Cited by 11937 |
Modification in reverse: the SUMO proteases
D Mukhopadhyay, M Dasso - Trends in biochemical sciences, 2007 - cell.com
SUMOs (small ubiquitin-like modifiers) are ubiquitin-related proteins that become covalently
conjugated to cellular target proteins that are involved in a variety of processes. Frequently, …
conjugated to cellular target proteins that are involved in a variety of processes. Frequently, …
The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110-and proteasome-dependent loss of several PML isoforms
RD Everett, P Freemont, H Saitoh, M Dasso… - Journal of …, 1998 - Am Soc Microbiol
The small nuclear structures known as ND10 or PML nuclear bodies have been implicated
in a variety of cellular processes including response to stress and interferons, oncogenesis, …
in a variety of cellular processes including response to stress and interferons, oncogenesis, …
[PDF][PDF] The ran GTPase regulates mitotic spindle assembly
Ran is an abundant nuclear GTPase with a clear role in nuclear transport during interphase [1]
but with roles in mitotic regulation that are less well understood [2]. The nucleotide-…
but with roles in mitotic regulation that are less well understood [2]. The nucleotide-…
[HTML][HTML] The cellular environment shapes the nuclear pore complex architecture
Nuclear pore complexes (NPCs) create large conduits for cargo transport between the
nucleus and cytoplasm across the nuclear envelope (NE) 1 , 2 – 3 . These multi-megadalton …
nucleus and cytoplasm across the nuclear envelope (NE) 1 , 2 – 3 . These multi-megadalton …
[HTML][HTML] The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo
RanGAP1 is the activating protein for the Ran GTPase. Vertebrate RanGAP1 is conjugated
to a small ubiquitin-like protein, SUMO-1 [1, 2]. This modification promotes association of …
to a small ubiquitin-like protein, SUMO-1 [1, 2]. This modification promotes association of …
SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles
RanGAP1 was the first documented substrate for conjugation with the ubiquitin-like protein
SUMO-1. However, the functional significance of this conjugation has not been fully clarified. …
SUMO-1. However, the functional significance of this conjugation has not been fully clarified. …
[HTML][HTML] Association of the human SUMO-1 protease SENP2 with the nuclear pore
J Hang, M Dasso - Journal of Biological Chemistry, 2002 - ASBMB
SUMO-1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins.
A family of proteases catalyzes deconjugation of SUMO-1-containing species. Members of …
A family of proteases catalyzes deconjugation of SUMO-1-containing species. Members of …
SUMOylation and deSUMOylation at a glance
Y Wang, M Dasso - Journal of cell science, 2009 - journals.biologists.com
Small ubiquitin-related modifiers (SUMOs) are ubiquitin-like polypeptides that become
covalently conjugated to cellular proteins in a manner similar to ubiquitylation (Johnson, 2004). …
covalently conjugated to cellular proteins in a manner similar to ubiquitylation (Johnson, 2004). …
Architecture of the cytoplasmic face of the nuclear pore
INTRODUCTION Cytoplasmic face of the human NPC. Near-atomic composite structure of
the NPC generated by docking high-resolution crystal structures into a cryo‑ET reconstruction …
the NPC generated by docking high-resolution crystal structures into a cryo‑ET reconstruction …
[PDF][PDF] The Ran GTPase: theme and variations
M Dasso - Current Biology, 2002 - cell.com
The small GTPase Ran has roles in multiple cellular processes, including nuclear transport,
mitotic spindle assembly, the regulation of cell cycle progression and nuclear assembly. The …
mitotic spindle assembly, the regulation of cell cycle progression and nuclear assembly. The …