purpose. In both animal model systems and in human glaucoma, retinal ganglion cells (RGCs)
die by apoptosis. To understand how RGC apoptosis is initiated in these systems, the …

purpose. To determine whether acute experimental glaucoma in rats obstructs retrograde
transport of brain-derived neurotrophic factor (BDNF) to retinal ganglion cells (RGCs). methods…

purpose. To develop a modified adenoassociated viral (AAV) vector capable of efficient
transfection of retinal ganglion cells (RGCs) and to test the hypothesis that use of this vector to …

methods. Experimental glaucoma was induced unilaterally in 174 Wistar rats, using a diode
laser with wavelength of 532 nm aimed at the trabecular meshwork and episcleral veins (…

purpose. Retinal ganglion cell (RGC) death in glaucoma involves apoptosis. Activation of
caspases and abnormal processing of amyloid precursor protein (APP) are important events in …

purpose. To compare the number of retinal ganglion cells (RGCs) topographically mapped
with specific visual field threshold test data in the same eyes among glaucoma patients. …

PURPOSE: To investigate whether retinal ganglion cell death in experimental glaucoma
and after axotomy occurs by apoptosis. METHODS: Chronic elevated eye pressure was …

purpose. To assess the neuroprotective effect of virally mediated overexpression of ciliary-derived
neurotrophic factor (CNTF) and brain-derived neurotrophic factor (BDNF) in …

purpose. To use a rat model of optic nerve injury to differentiate primary and secondary retinal
ganglion cell (RGC) injury. methods. Under general anesthesia, a modified diamond knife …

Objective: To determine whether retinal ganglion cell death in primary open-angle glaucoma
occurs by apoptosis. Methods: Eighteen eyes of 17 subjects with documented primary open…