Background There is a scarcity of published data on the global prevalence of obstructive
sleep apnoea, a disorder associated with major neurocognitive and cardiovascular sequelae. …

Objective: Obstructive sleep apnea (OSA) causes hypoxemia and fragmented sleep, which
lead to neurocognitive deficits. We hypothesised that focal loss of cortical gray matter …

Intermittent hypoxia, reoxygenation, and hypercapnia or hypocapnia occur in both adults and
children during untreated apnoea and hypopnoea, along with changes in cerebral blood …

Background The therapeutic and economic benefits of continuous positive airway pressure (CPAP)
for moderate to severe obstructive sleep apnoea (OSA) syndrome have been …

Alzheimer’s disease (AD) and obstructive sleep apnea (OSA) are highly prevalent, chronic
conditions with intriguing, yet poorly understood epidemiological overlap. To date, the …

Rationale: Obesity increases the risk and severity of sleep-disordered breathing. The degree
to which excess body weight contributes to blood oxygen desaturation during hypopneic …

Sleep deprivation is common among university students, and has been associated with poor
academic performance and physical dysfunction. However, current literature has a narrow …

… Correspondence and requests for reprints should be addressed to Mary J. Morrell, Sleep
and Ventilation Unit, Royal Brompton Hospital (South Block), Sydney Street, London SW3 6NP, …

Future health systems require the means to assess and track the neural and physiological
function of a user over long periods of time, and in the community. Human body responses are …

Pharyngeal occlusion during obstructive apnea is thought to be an inspiratory-related event;
however, occlusion also occurs in the absence of negative intrathoracic pressure. We …