The major barrier to research and development of effective interventions for human noroviruses
(HuNoVs) has been the lack of a robust and reproducible in vitro cultivation system. …

Noroviruses are now recognized as the leading cause of epidemics of gastroenteritis and
an important cause of sporadic gastroenteritis among both children and adults. In the United …

Knowledge of the structure and function of the genes and proteins of the rotaviruses has
expanded rapidly. Information obtained in the last 5 years has revealed unexpected and unique …

Noroviruses (NoVs) are a leading cause of gastroenteritis worldwide and are recognized as
the foremost cause of foodborne illness. Despite numerous efforts, routine cell cultures have …

Norwalk virus, a noncultivatable human calicivirus, is the major cause of epidemic gastroenteritis
in humans. The first x-ray structure of a calicivirus capsid, which consists of 180 copies …

Major epidemic outbreaks of acute gastroenteritis result from infections with Norwalk or
Norwalk-like viruses. Virus purified from stool specimens of volunteers experimentally infected …

Noroviruses are the most common cause of viral gastroenteritis in the United States. To
determine the magnitude and duration of virus shedding in feces, we evaluated persons who …

Some people are resistant to Norwalk virus (NV) infection; however, the factor(s)
responsible for resistance or susceptibility to NV infection has not been identified. This study …

Background Rotavirus is the leading cause of severe diarrhea in infants. To provide a base
line for assessing the efficacy of rotavirus vaccines, we evaluated the protection that is …

In April 2008, a nucleotide-sequence-based, complete genome classification system was
developed for group A rotaviruses (RVs). This system assigns a specific genotype to each of …